Ivan V Zelepukin
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Explore the profile of Ivan V Zelepukin including associated specialties, affiliations and a list of published articles.
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23
Citations
273
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Recent Articles
1.
Belyaev I, Griaznova O, Yaremenko A, Deyev S, Zelepukin I
Adv Drug Deliv Rev
. 2025 Feb;
219:115550.
PMID: 40021012
Delivery of nanoparticles (NPs) to solid tumors has long relied on enhanced permeability and retention (EPR) effect, involving permeation of NPs through a leaky vasculature with prolonged retention by reduced...
2.
Krylova L, Otvagin V, Gribova G, Kuzmina N, Fedotova E, Zelepukin I, et al.
J Med Chem
. 2025 Jan;
68(2):1901-1923.
PMID: 39743785
In this report, we developed novel chlorin/arylaminoquinazoline conjugates for targeted photodynamic therapy of cancer. The synthesized photosensitizers consisted of chlorin- metallocomplexes (Zn, In, or Pd) conjugated with arylaminoquinazoline ligands with...
3.
Belyaev I, Mirkasymov A, Rodionov V, Babkova J, Nikitin P, Deyev S, et al.
Biomed Mater
. 2024 Sep;
19(6).
PMID: 39312951
Pharmacokinetics of nanomedicines can be improved by a temporal blockade of mononuclear phagocyte system (MPS) through the interaction with other biocompatible nanoparticles. Liposomes are excellent candidates as blocking agents, but...
4.
Popov A, Kolmanovich D, Chukavin N, Zelepukin I, Tikhonowski G, Pastukhov A, et al.
Molecules
. 2024 Aug;
29(16).
PMID: 39203014
Boron-enhanced proton therapy has recently appeared as a promising approach to increase the efficiency of proton therapy on tumor cells, and this modality can further be improved by the use...
5.
Zelepukin I, Shevchenko K, Deyev S
Nat Commun
. 2024 May;
15(1):4366.
PMID: 38777821
Rapid uptake of nanoparticles by mononuclear phagocyte system (MPS) significantly hampers their therapeutic efficacy. Temporal MPS blockade is one of the few ways to overcome this barrier - the approach...
6.
Belyaev I, Zelepukin I, Kotelnikova P, Tikhonowski G, Popov A, Kapitannikova A, et al.
Adv Sci (Weinh)
. 2024 Mar;
11(20):e2307060.
PMID: 38516744
Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical applications. Ge NPs...
7.
Zavestovskaya I, Kasatova A, Kasatov D, Babkova J, Zelepukin I, Kuzmina K, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069412
Boron neutron capture therapy (BNCT) is one of the most appealing radiotherapy modalities, whose localization can be further improved by the employment of boron-containing nanoformulations, but the fabrication of biologically...
8.
Belyaev I, Zelepukin I, Tishchenko V, Petriev V, Trushina D, Klimentov S, et al.
Nanotechnology
. 2023 Nov;
35(7).
PMID: 37963406
Nuclear medicine presents one of the most promising modalities for efficient non-invasive treatment of a variety of cancers, but the application of radionuclides in cancer therapy and diagnostics is severely...
9.
Zavestovskaya I, Popov A, Kolmanovich D, Tikhonowski G, Pastukhov A, Savinov M, et al.
Nanomaterials (Basel)
. 2023 Aug;
13(15).
PMID: 37570485
Proton therapy is one of the promising radiotherapy modalities for the treatment of deep-seated and unresectable tumors, and its efficiency can further be enhanced by using boron-containing substances. Here, we...
10.
Yaremenko A, Zelepukin I, Ivanov I, Melikov R, Pechnikova N, Dzhalilova D, et al.
J Nanobiotechnology
. 2022 Dec;
20(1):535.
PMID: 36528614
Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their contrast properties and...