Ivan Mendez-Lopez
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Explore the profile of Ivan Mendez-Lopez including associated specialties, affiliations and a list of published articles.
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10
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204
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Recent Articles
1.
Erviti J, Saiz L, Leache L, Pijoan J, Menendez Orenga M, Salzwedel D, et al.
Cochrane Database Syst Rev
. 2024 Oct;
10:CD008564.
PMID: 39403990
Background: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease, development of end-stage renal disease, and all-cause mortality. It affects around 10% of the population worldwide. The...
2.
Acha B, Corroza J, de Gordoa J, Cabello C, Robles M, Mendez-Lopez I, et al.
Neurology
. 2023 Oct;
101(23):e2434-e2447.
PMID: 37827850
Background And Objectives: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising...
3.
Blanco-Luquin I, Acha B, Urdanoz-Casado A, de Gordoa J, Vicuna-Urriza J, Roldan M, et al.
Epigenetics
. 2020 Apr;
15(10):1083-1092.
PMID: 32233750
Abbreviations: AD: Alzheimer's disease; DMPs: Differentially methylated positions; CSF: Cerebrospinal fluid; βA42: β-amyloid 42; PET: positron emission tomography; 5mC: 5-methyl cytosine; CpG: cytosine-guanine dinucleotides; : ankyrin-1; : amphiphysin II; p-tau:...
4.
Altuna M, Urdanoz-Casado A, de Gordoa J, Zelaya M, Labarga A, Lepesant J, et al.
Clin Epigenetics
. 2019 Jun;
11(1):91.
PMID: 31217032
Background: Drawing the epigenome landscape of Alzheimer's disease (AD) still remains a challenge. To characterize the epigenetic molecular basis of the human hippocampus in AD, we profiled genome-wide DNA methylation...
5.
Mendez-Lopez I, Blanco-Luquin I, de Gordoa J, Urdanoz-Casado A, Roldan M, Acha B, et al.
Int J Mol Sci
. 2019 Feb;
20(4).
PMID: 30781626
Lamins are fibrillary proteins that are crucial in maintaining nuclear shape and function. Recently, B-type lamin dysfunction has been linked to tauopathies. However, the role of A-type lamin in neurodegeneration...
6.
Shin J, Mendez-Lopez I, Hong M, Wang Y, Tanji K, Wu W, et al.
Hum Mol Genet
. 2016 Nov;
26(1):65-78.
PMID: 27798115
Lamina-associated polypeptide 1 (LAP1) is an integral protein of the inner nuclear membrane that has been implicated in striated muscle maintenance. Mutations in its gene have been linked to muscular...
7.
Mendioroz Iriarte M, Pulido Fontes L, Mendez-Lopez I
Med Clin (Barc)
. 2014 Jun;
144(10):457-64.
PMID: 24907105
DNA methylation is an epigenetic mechanism that controls gene expression. In Alzheimer's disease (AD), global DNA hypomethylation of neurons has been described in the human cerebral cortex. Moreover, several variants...
8.
Shin J, Mendez-Lopez I, Wang Y, Hays A, Tanji K, Lefkowitch J, et al.
Dev Cell
. 2013 Sep;
26(6):591-603.
PMID: 24055652
X-linked Emery-Dreifuss muscular dystrophy is caused by loss of function of emerin, an integral protein of the inner nuclear membrane. Yet emerin null mice are essentially normal, suggesting the existence...
9.
Mendez-Lopez I, Worman H
Chromosoma
. 2012 Feb;
121(2):153-67.
PMID: 22307332
In the past decade, the inner nuclear membrane has become a focus of research on inherited diseases. A heterogeneous group of genetic disorders known as laminopathies have been described that...
10.
Mendez-Lopez I
Med Clin (Barc)
. 2011 Jun;
138(5):208-14.
PMID: 21632068
Laminopathies are a group of diseases that share wrong codification of lamins, building proteins of the nuclear lamina. Different tissues are affected in those disorders: striated muscle, adipose tissue, central...