Istvan Vincze
Overview
Explore the profile of Istvan Vincze including associated specialties, affiliations and a list of published articles.
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20
Citations
55
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Recent Articles
1.
Feher A, Vincze I, Rudge J, Domjan G, Vasarhelyi B, Karvaly G
Diagnostics (Basel)
. 2024 Sep;
14(17).
PMID: 39272725
Our aim was to compare the performance of complementary clinical laboratory approaches to monitoring exposure to apixaban and rivaroxaban, the most prescribed direct-acting oral anticoagulants (DOAC's): an automated commercial anti-Xa...
2.
Karvaly G, Vincze I, Neely M, Zatroch I, Nagy Z, Kocsis I, et al.
Pharmaceutics
. 2024 Mar;
16(3).
PMID: 38543252
Population pharmacokinetic (pop-PK) models constructed for model-informed precision dosing often have limited utility due to the low number of patients recruited. To augment such models, an approach is presented for...
3.
Kollo Z, Garami M, Vincze I, Vasarhelyi B, Karvaly G
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678867
Orally administered, small-molecule anticancer drugs with tumor-specific cellular protein targets (OACD) have revolutionized oncological pharmacotherapy. Nevertheless, the differences in exposure to these drugs in the systemic circulation and extravascular fluid...
4.
Karvaly G, Vincze I, Balogh A, Kollo Z, Bodor C, Vasarhelyi B
Molecules
. 2022 Jul;
27(15).
PMID: 35897942
Ibrutinib (IBR) is an oral anticancer medication that inhibits Bruton tyrosine kinase irreversibly. Due to the high risk of adverse effects and its pharmacokinetic variability, the safe and effective use...
5.
Vincze I, Czermann R, Nagy Z, Kovacs M, Neely M, Farkas R, et al.
J Clin Med
. 2022 Jul;
11(14).
PMID: 35887904
Severe community-acquired pneumonia (CAP) is a condition that frequently requires intensive care and, eventually, can cause to death. Piperacillin/tazobactam antibiotic therapy is employed as an empiric intravenous regimen, in many...
6.
Karvaly G, Karadi I, Vincze I, Neely M, Trojnar E, Prohaszka Z, et al.
Pharmacol Res Perspect
. 2021 Sep;
9(5):e00856.
PMID: 34478238
The inadequate adherence of patients whose hyperlipidemia is treated with atorvastatin (ATR) to medical instructions presents a serious health risk. Our aim was to develop a flexible approach based on...
7.
Karvaly G, Vincze I, Karadi I, Vasarhelyi B, Zsary A
Molecules
. 2021 Apr;
26(5).
PMID: 33801290
The antihyerlipidemic drug atorvastatin (ATR) is used worldwide as part of the strategy to prevent cardiovascular events. The high prevalence of patient nonadherence remains an important challenge which could be...
8.
Bagamery F, Varga K, Kecsmar K, Vincze I, Szoko E, Tabi T
Neurochem Res
. 2021 Feb;
46(6):1350-1358.
PMID: 33616807
Recently neuronal insulin resistance was suggested playing a role in Alzheimer's disease. Streptozotocin (STZ) is commonly used to induce impairment in insulin metabolism. In our previous work on undifferentiated SH-SY5Y...
9.
Vincze I, Rudge J, Vasarhelyi B, Karvaly G
Bioanalysis
. 2020 Sep;
12(17):1243-1261.
PMID: 32915068
Multiplexed, high-throughput analysis facilitates therapeutic drug monitoring. 14 drugs with various physico-chemical properties were quantitated in dried blood microsamples. Analytes were extracted employing eight solvent compositions and seven extraction methods....
10.
Lakatos P, Vincze I, Nyariki N, Bagamery F, Tabi T, Szoko E
Biochim Biophys Acta Proteins Proteom
. 2020 Jun;
1868(10):140473.
PMID: 32574765
Decreased extracellular level of d-Serine (D-Ser), a co-agonist of the N-methyl-d-aspartate (NMDA) receptors was connected to receptor hypofunction in the brain and the related deficit of cognitive functions. Extracellular D-Ser...