Issam Makhoul
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Explore the profile of Issam Makhoul including associated specialties, affiliations and a list of published articles.
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85
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823
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Recent Articles
1.
Todorova V, Azhar G, Stone A, Malapati S, Che Y, Zhang W, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273682
Doxorubicin (DOX), a commonly used anticancer agent, causes cardiotoxicity that begins with the first dose and may progress to heart failure years after treatment. An inflammatory response associated with neutrophil...
2.
Makhoul I, Power S, Smith C, Niece T, OMahony D
JCO Glob Oncol
. 2024 Aug;
10:e2400058.
PMID: 39159411
A growing sense of the need to define good-quality cancer care has emerged in the past decade of the 20th century. The goals were to assess, improve, and reward quality....
3.
Todorova V, Byrum S, Mackintosh S, Jamshidi-Parsian A, Gies A, Washam C, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685904
Infection with hepatitis B virus (HBV) is a main risk factor for hepatocellular carcinoma (HCC). Extracellular vesicles, such as exosomes, play an important role in tumor development and metastasis, including...
4.
Power S, Bickel K, Chen R, Chiang A, Garrett-Mayer L, Makhoul I, et al.
JCO Oncol Pract
. 2023 Jan;
19(4):e520-e526.
PMID: 36669136
Purpose: Despite the growing calls for early and ubiquitous completion of advance directives (ADs), studies exploring links between AD completion and their impact on outcomes of patients with cancer have...
5.
Baltz A, Siegel E, Kamal A, Siegel R, Kozlik M, Crist S, et al.
JCO Oncol Pract
. 2022 Nov;
19(2):e274-e285.
PMID: 36375114
Purpose: American Society for Clinical Oncology released the Choosing Wisely list in 2012, highlighting low-value procedures that lack evidence, advising against the use of positron emission tomography, computerized tomography, and...
6.
Pashov A, Murali R, Makhoul I, Karbassi B, Kieber-Emmons T
Monoclon Antib Immunodiagn Immunother
. 2022 Oct;
41(5):290-300.
PMID: 36306515
Targeting the diverse glycan repertoire expressed on tumor cells is considered a viable therapeutic strategy to deal with tumor cell heterogeneity. Inherently polyspecific, natural, glycan-reactive antibodies are purported to be...
7.
Makhoul I, Anders M, Siegel R, Chiang A, Markham M, Chen R, et al.
JCO Oncol Pract
. 2022 Apr;
18(7):e1209-e1218.
PMID: 35467961
Purpose: In the first decade of this millennium, ASCO pioneered a quality measurement tool, the Quality Oncology Practice Initiative (QOPI). Despite an Accreditation Council for Graduate Medical Education (ACGME) requirement...
8.
Chen R, Garrett-Mayer E, Kamal A, Makhoul I, Kozlik M, Crist S, et al.
JCO Oncol Pract
. 2022 Mar;
18(8):e1367-e1373.
PMID: 35353546
Purpose: For patients with nonmetastatic rectal cancer, the National Comprehensive Cancer Network guidelines recommend initial staging using pelvic magnetic resonance imaging or endorectal ultrasound to determine the stage of the...
9.
Todorova V, Byrum S, Gies A, Haynie C, Smith H, Reyna N, et al.
Curr Oncol
. 2022 Feb;
29(2):613-630.
PMID: 35200555
Background: Neoadjuvant chemotherapy (NACT) is an increasingly used approach for treatment of breast cancer. The pathological complete response (pCR) is considered a good predictor of disease-specific survival. This study investigated...
10.
Eisen A, Somerfield M, Accordino M, Blanchette P, Clemons M, Dhesy-Thind S, et al.
J Clin Oncol
. 2022 Jan;
40(7):787-800.
PMID: 35041467
Purpose: To update recommendations of the American Society of Clinical Oncology (ASCO)-Ontario Health (Cancer Care Ontario [CCO]) adjuvant bone-modifying agents in breast cancer guideline. Methods: An Expert Panel conducted a...