Ismail Hermelo
Overview
Explore the profile of Ismail Hermelo including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
80
Followers
0
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Recent Articles
1.
Hermelo I, Virtanen T, Salonen I, Natkin R, Keitaanniemi S, Tiihonen A, et al.
Cancer Immunol Immunother
. 2025 Jan;
74(2):63.
PMID: 39751910
The tumor immune microenvironment (TiME) of human central nervous system (CNS) tumors remains to be comprehensively deciphered. Here, we employed flow cytometry and RNA sequencing analysis for a deep data-driven...
2.
Hermelo I, Haapala I, Makela M, Jacome Sanz D, Kontunen A, Karjalainen M, et al.
J Neurooncol
. 2024 Nov;
171(3):691-703.
PMID: 39578301
Purpose: Extent of brain tumor resection continues to be one of the central decisions taken during standard of care in glioma patients. Here, we aimed to evaluate the most essential...
3.
Kiviaho A, Eerola S, Kallio H, Andersen M, Hoikka M, Tiihonen A, et al.
Nat Commun
. 2024 Nov;
15(1):9949.
PMID: 39550375
Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation toward...
4.
Ortutay Z, Gronholm A, Laitinen M, Keresztes-Andrei M, Hermelo I, Pesu M
Front Immunol
. 2021 Mar;
12:630389.
PMID: 33679774
The proprotein convertase enzyme FURIN promotes the proteolytic maturation of pro-proteins and thereby it serves as an important factor for maintaining cellular homeostasis. In T cells, FURIN is critical for...
5.
Luoto S, Hermelo I, Vuorinen E, Hannus P, Kesseli J, Nykter M, et al.
Cancer Res
. 2018 Jun;
78(19):5574-5585.
PMID: 29921698
The immunosuppressive microenvironment in glioblastoma (GBM) prevents an efficient antitumoral immune response and enables tumor formation and growth. Although an understanding of the nature of immunosuppression is still largely lacking,...
6.
Segarra-Mondejar M, Casellas-Diaz S, Ramiro-Pareta M, Muller-Sanchez C, Martorell-Riera A, Hermelo I, et al.
EMBO J
. 2018 Apr;
37(9).
PMID: 29615453
The formation of neurites is an important process affecting the cognitive abilities of an organism. Neurite growth requires the addition of new membranes, but the metabolic remodeling necessary to supply...
7.
Bueno D, Parvas M, Hermelo I, Garcia-Fernandez J
Front Neurosci
. 2014 Nov;
8:343.
PMID: 25389383
During embryonic development and adult life, brain cavities and ventricles are filled with cerebrospinal fluid (CSF). CSF has attracted interest as an active signaling medium that regulates brain development, homeostasis...