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Ishita Singh

Explore the profile of Ishita Singh including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 86
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Recent Articles
1.
Wang T, Dollahon C, Mishra S, Patel H, Abolghasemzade S, Singh I, et al.
NPJ Precis Oncol . 2024 Dec; 8(1):276. PMID: 39623008
Nuclear atypia is a hallmark of cancer. A recent model posits that excess surface area, visible as folds/wrinkles in the lamina of a rounded nucleus, allows the nucleus to take...
2.
Wang T, Abolghasemzade S, McKee B, Singh I, Pendyala K, Mohajeri M, et al.
Nat Commun . 2024 Nov; 15(1):10151. PMID: 39578439
Extracellular matrix (ECM) stiffness influences cancer cell fate by altering gene expression. Previous studies suggest that stiffness-induced nuclear deformation may regulate gene expression through YAP nuclear localization. We investigated the...
3.
Singh I, Li X, Iafolla T, Boroumand S, Alraqiq H
J Public Health Dent . 2024 Sep; 84(4):439-452. PMID: 39253777
Objective: Individuals with disabilities face elevated risks of adverse oral health outcomes compared with the general population, including worse periodontal health, increased edentulism, and untreated dental decay. Given the varied...
4.
Winkler J, Dixon B, Singh I, Soto R, Qiu Y, Zhang Y, et al.
BMC Oral Health . 2024 Mar; 24(1):326. PMID: 38468230
Environmental toxins are known to have many impacts on growth and development in humans, starting in utero. Alterations in amelogenesis, caused by chemical and physical trauma that occur during the...
5.
Singh I, Lele T
Results Probl Cell Differ . 2022 Nov; 70:443-467. PMID: 36348118
Irregularities in nuclear shape and/or alterations to nuclear size are a hallmark of malignancy in a broad range of cancer types. Though these abnormalities are commonly used for diagnostic purposes...
6.
Atkinson E, Kuliasha C, Kasper M, Furniturewalla A, Lim A, Jiracek-Sapieha L, et al.
J Neural Eng . 2022 Aug; 19(5). PMID: 35998559
. Although neural-enabled prostheses have been used to restore some lost functionality in clinical trials, they have faced difficulty in achieving high degree of freedom, natural use compared to healthy...
7.
Kasper M, Ellenbogen B, Hardy R, Cydis M, Mojica-Santiago J, Afridi A, et al.
Biomaterials . 2021 Oct; 279:121212. PMID: 34717196
Peripheral nerve injuries can be debilitating to motor and sensory function, with severe cases often resulting in complete limb amputation. Over the past two decades, prosthetic limb technology has rapidly...
8.
Sen K, Sheppe A, Singh I, Hui W, Edelmann M, Rinaldi C
Int J Hyperthermia . 2020 Jun; 37(1):696-710. PMID: 32568583
Macrophages play a dual role in tumor initiation and progression, with both tumor-promoting and tumor-suppressive effects; hence, it is essential to understand the distinct responses of macrophages to tumor progression...
9.
Singh I, Lacko C, Zhao Z, Schmidt C, Rinaldi C
J Colloid Interface Sci . 2019 Nov; 561:647-658. PMID: 31761469
Our aim is to develop a hydrogel-based scaffold containing porous microchannels that mimic complex tissue microarchitecture and provide physical cues to guide cell growth for scalable, cost-effective tissue repair. These...
10.
Lacko C, Singh I, Wall M, Garcia A, Porvasnik S, Rinaldi C, et al.
J Neural Eng . 2019 Oct; 17(1):016057. PMID: 31577998
Objective: Hydrogel scaffolds hold promise for a myriad of tissue engineering applications, but often lack tissue-mimetic architecture. Therefore, in this work, we sought to develop a new technology for the...