Isabelle Vachier
Overview
Explore the profile of Isabelle Vachier including associated specialties, affiliations and a list of published articles.
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93
Citations
1084
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Recent Articles
11.
Bourdin A, Bommart S, Marin G, Vachier I, Gamez A, Ahmed E, et al.
Allergy
. 2022 Sep;
78(3):780-790.
PMID: 36070075
Background: Obesity is known to diminish lung volumes and worsen asthma. However, mechanistic understanding is lacking, especially as concerns small-airway responsiveness. The objective of this study was therefore to compare...
12.
Ahmed E, Fieldes M, Bourguignon C, Mianne J, Petit A, Jory M, et al.
Cells
. 2022 Aug;
11(15).
PMID: 35954266
Background: Chronic Obstructive Pulmonary Disease (COPD), a major cause of mortality and disability, is a complex disease with heterogeneous and ill-understood biological mechanisms. Human induced pluripotent stem cells (hiPSCs) are...
13.
Volpato M, Vialaret J, Hirtz C, Petit A, Suehs C, Patarin J, et al.
Biochem Biophys Res Commun
. 2022 Jul;
622:64-71.
PMID: 35843096
Background: Mucus is known to play a pathogenic role in muco-obstructive lung diseases, but little is known about the determinants of mucus rheology. The purpose of this study is to...
14.
Eger K, Paroczai D, Bacon A, Schleich F, Sergejeva S, Bourdin A, et al.
ERJ Open Res
. 2022 May;
8(2).
PMID: 35582679
Background: The coronavirus disease 2019 (COVID-19) pandemic has put pressure on healthcare services, forcing the reorganisation of traditional care pathways. We investigated how physicians taking care of severe asthma patients...
15.
Using intracellular SCGB1A1-sorted, formalin-fixed club cells for successful transcriptomic analysis
Vernisse C, Petit A, Pantesco V, Chanez P, Gras D, Tuaillon E, et al.
Biochem Biophys Res Commun
. 2022 Mar;
604:151-157.
PMID: 35305419
As opposed to surface marker staining, certain cell types can only be recognized by intracellular markers. Intracellular staining for use in cell sorting remains challenging. Fixation and permeabilization steps for...
16.
Charriot J, Volpato M, Petit A, Vachier I, Bourdin A
Cells
. 2022 Mar;
11(5).
PMID: 35269434
Obstructive lung diseases, such as chronic obstructive pulmonary disease, asthma, or non-cystic fibrosis bronchiectasis, share some major pathophysiological features: small airway involvement, dysregulation of adaptive and innate pulmonary immune homeostasis,...
17.
Nasri A, Foisset F, Ahmed E, Lahmar Z, Vachier I, Jorgensen C, et al.
Cells
. 2021 Dec;
10(12).
PMID: 34943975
Mesenchymal cells are an essential cell type because of their role in tissue support, their multilineage differentiation capacities and their potential clinical applications. They play a crucial role during lung...
18.
Ahmed E, Fieldes M, Mianne J, Bourguignon C, Nasri A, Vachier I, et al.
Stem Cell Res
. 2021 Oct;
56:102550.
PMID: 34624616
Evidence highlights the concept of multiple trajectories leading to COPD. Early-life events (i.e., in utero lung development) may influence the maximally attained lung function and increase the risk to develop...
19.
Halimi L, Suehs C, Marin G, Boissin C, Gamez A, Vachier I, et al.
ERJ Open Res
. 2021 Aug;
7(3).
PMID: 34435036
Objectives: The role of health-related quality of life (HRQoL) and psychological variables in pulmonary arterial hypertension (PAH) progression remains poorly quantified. We aimed to investigate the relationship between disease progression...
20.
Suehs C, Solovei L, Hireche K, Vachier I, Goulart D, Gamon L, et al.
Ann Transl Med
. 2021 Aug;
9(13):1092.
PMID: 34423004
Background: Recent advancements in computed tomography (CT) scanning and post processing have provided new means of assessing factors affecting respiratory function. For lung cancer patients requiring resection, and especially those...