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Isabelle St-Amour

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Articles 38
Citations 1129
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Recent Articles
1.
Nateghi B, Keraudren R, Boulay G, Bazin M, Goupil C, Canet G, et al.
Front Neurosci . 2024 Aug; 18:1421680. PMID: 39170678
Huntington's disease (HD) is a rare genetic neurodegenerative disorder caused by an expansion of CAG repeats in the Huntingtin (HTT) gene. One hypothesis suggests that the mutant HTT gene contributes...
2.
Petry S, Keraudren R, Nateghi B, Loiselle A, Pircs K, Jakobsson J, et al.
Acta Neuropathol Commun . 2022 Jul; 10(1):106. PMID: 35869509
Altered microRNA (miRNA) expression is a common feature of Huntington's disease (HD) and could participate in disease onset and progression. However, little is known about the underlying causes of miRNA...
3.
Petry S, Nateghi B, Keraudren R, Sergeant N, Planel E, Hebert S, et al.
Neuroscience . 2022 Jul; 518:54-63. PMID: 35868517
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by an expansion of CAG repeats in the Huntingtin (HTT) gene. Accumulating evidence suggests that the microtubule-associated tau protein participates in...
4.
Pircs K, Drouin-Ouellet J, Horvath V, Gil J, Rezeli M, Garza R, et al.
Brain . 2021 Dec; 145(9):3035-3057. PMID: 34936701
Huntington's disease is a neurodegenerative disorder caused by CAG expansions in the huntingtin (HTT) gene. Modelling Huntington's disease is challenging, as rodent and cellular models poorly recapitulate the disease as...
5.
Boscher E, Hernandez-Rapp J, Petry S, Keraudren R, Rainone S, Loiselle A, et al.
Front Neurol . 2020 Oct; 11:578720. PMID: 33117266
In the past decade, several groups have reported that microRNAs (miRNAs) can participate in the regulation of tau protein at different levels, including its expression, alternative splicing, phosphorylation, and aggregation....
6.
Gagne A, Moreau I, St-Amour I, Marquet P, Maziade M
Schizophr Res . 2019 Jul; 219:19-24. PMID: 31320175
Background: Visual defects are documented in psychiatric disorders such as schizophrenia, bipolar disorder and major depressive disorder. One of the most consistent alterations in patients is a change in cone...
7.
St-Amour I, Bosoi C, Pare I, Doss P, Rangachari M, Hebert S, et al.
J Neuroinflammation . 2019 Jan; 16(1):3. PMID: 30611289
Background: Immunologic abnormalities have been described in peripheral blood and central nervous system of patients suffering from Alzheimer's disease (AD), yet their role in the pathogenesis still remains poorly defined....
8.
Denis H, Lamontagne-Proulx J, St-Amour I, Mason S, Rowley J, Cloutier N, et al.
J Neurol Neurosurg Psychiatry . 2018 Dec; 90(3):272-283. PMID: 30567722
Objectives: Seeking to elucidate the origin of these vascular and BBB abnormalities, we studied platelets that are known to play a role in maintaining the integrity of the vasculature and...
9.
Lamontagne-Proulx J, St-Amour I, Labib R, Pilon J, Denis H, Cloutier N, et al.
Neurobiol Dis . 2018 Nov; 124:163-175. PMID: 30408591
The production of extracellular vesicles (EV) is a ubiquitous feature of eukaryotic cells but pathological events can affect their formation and constituents. We sought to characterize the nature, profile and...
10.
Denis H, Lamontagne-Proulx J, St-Amour I, Mason S, Weiss A, Chouinard S, et al.
J Neurol . 2018 Sep; 265(11):2704-2712. PMID: 30209650
The production and release of extracellular vesicles (EV) is a property shared by all eukaryotic cells and a phenomenon frequently exacerbated in pathological conditions. The protein cargo of EV, their...