Isabelle Roth
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Explore the profile of Isabelle Roth including associated specialties, affiliations and a list of published articles.
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25
Citations
593
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Recent Articles
11.
Feraille E, Dizin E, Roth I, Derouette J, Szanto I, Martin P, et al.
PLoS One
. 2014 Jan;
9(1):e87239.
PMID: 24466344
The final control of renal water reabsorption occurs in the collecting duct (CD) and relies on regulated expression of aquaporin-2 (AQP2) in principal CD cells. AQP2 transcription is primarily induced...
12.
Dizin E, Hasler U, Nlandu-Khodo S, Fila M, Roth I, Ernandez T, et al.
Am J Physiol Renal Physiol
. 2013 Jul;
305(7):F1053-63.
PMID: 23884139
Albuminuria is strongly associated with progressive kidney tubulo-interstitial damage and chronic kidney disease (CKD) progression. In proteinuric nephropathies, albumin reabsorption by the proximal tubule is saturated and the distal nephron...
13.
Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, et al.
Autophagy
. 2013 Feb;
9(4):550-67.
PMID: 23380587
Osmotic homeostasis is fundamental for most cells, which face recurrent alterations of environmental osmolality that challenge cell viability. Protein damage is a consequence of hypertonic stress, but whether autophagy contributes...
14.
Angelillo-Scherrer A, Fontana P, Burnier L, Roth I, Sugamele R, Brisset A, et al.
Circulation
. 2011 Aug;
124(8):930-9.
PMID: 21810657
Background: Formation of platelet plug initiates hemostasis after vascular injury and triggers thrombosis in ischemic disease. However, the mechanisms leading to the formation of a stable thrombus are poorly understood....
15.
Morel S, Burnier L, Roatti A, Chassot A, Roth I, Sutter E, et al.
Carcinogenesis
. 2010 Aug;
31(11):1922-31.
PMID: 20705954
Connexins are a large family of proteins that form gap junction channels allowing exchange of ions and small metabolites between neighboring cells. They have been implicated in pathological processes such...
16.
Roth I, Leroy V, Kwon H, Martin P, Feraille E, Hasler U
Mol Biol Cell
. 2010 Aug;
21(19):3459-74.
PMID: 20685965
Tonicity-responsive binding-protein (TonEBP or NFAT5) is a widely expressed transcription factor whose activity is regulated by extracellular tonicity. TonEBP plays a key role in osmoprotection by binding to osmotic response...
17.
Pfenniger A, Derouette J, Verma V, Lin X, Foglia B, Coombs W, et al.
Arterioscler Thromb Vasc Biol
. 2010 Jan;
30(4):827-34.
PMID: 20081116
Objective: The gap junction protein connexin37 (Cx37) plays an important role in cell-cell communication in the vasculature. A C1019T Cx37 gene polymorphism, encoding a P319S substitution in the regulatory C...
18.
Derouette J, Wong C, Burnier L, Morel S, Sutter E, Galan K, et al.
Atherosclerosis
. 2009 Apr;
206(1):69-76.
PMID: 19345950
Recently, we showed that connexin37 (Cx37) protects against early atherosclerotic lesion development by regulating monocyte adhesion. The expression of this gap junction protein is altered in mouse and human atherosclerotic...
19.
Derouette J, Desplantez T, Wong C, Roth I, Kwak B, Weingart R
J Mol Cell Cardiol
. 2009 Jan;
46(4):499-507.
PMID: 19166859
A polymorphism in the human Cx37 gene (C1019T), resulting in a non-conservative amino acid change in the regulatory C-terminus of the Cx37 protein (P319S), has been proposed as a prognostic...
20.
Chadjichristos C, Morel S, Derouette J, Sutter E, Roth I, Brisset A, et al.
Circ Res
. 2008 Feb;
102(6):653-60.
PMID: 18239136
We previously reported that reducing the expression of the gap junction protein connexin (Cx)43 in mice restricts intimal thickening formation after acute vascular injury by limiting the inflammatory response and...