Isabelle Leclercq
Overview
Explore the profile of Isabelle Leclercq including associated specialties, affiliations and a list of published articles.
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57
Citations
1903
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Recent Articles
11.
Maccioni L, Gao B, Leclercq S, Pirlot B, Horsmans Y, de Timary P, et al.
Gut Microbes
. 2020 Jun;
12(1):1782157.
PMID: 32588725
Background: Animal data suggest a role of the gut-liver axis in progression of alcoholic liver disease (ALD), but human data are scarce especially for early disease stages. Methods: We included...
12.
Lefort C, Roumain M, Van Hul M, Rastelli M, Manco R, Leclercq I, et al.
Cells
. 2020 May;
9(5).
PMID: 32443626
Diverse metabolic disorders have been associated with an alteration of -acylethanolamine (NAE) levels. These bioactive lipids are synthesized mainly by -acylphosphatidylethanolamine-selective phospholipase D (NAPE-PLD) and influence host metabolism. We have...
13.
Minsart C, Liefferinckx C, Lemmers A, Dressen C, Quertinmont E, Leclercq I, et al.
Sci Rep
. 2020 Mar;
10(1):5557.
PMID: 32221312
Extracellular release of HMGB1 contributes to acetaminophen-induced liver injury. HMGB1 acts as a danger-associated molecular patterns during this toxic process but the mechanisms of action and targeted cells are incompletely...
14.
Duchene G, Abarca-Quinones J, Feza-Bingi N, Leclercq I, Duprez T, Peeters F
J Magn Reson Imaging
. 2020 Mar;
52(3):941-951.
PMID: 32147929
Background: Microstructure analyses are gaining interest in cancer MRI as an alternative to the conventional apparent diffusion coefficient (ADC), of which the determinants remain unclear. Purpose: To assess the sensitivity...
15.
Duchene G, Abarca-Quinones J, Leclercq I, Duprez T, Peeters F
Magn Reson Med
. 2019 Oct;
83(4):1263-1276.
PMID: 31593350
Purpose: To present a double diffusion encoding MRI sequence on a clinical scanner to analyze micro-structure and micro-vasculature of tumors. Methods: The sequence was tested on phantoms, asparaguses, and 2...
16.
Czepukojc B, Abuhaliema A, Barghash A, Tierling S, Nass N, Simon Y, et al.
Front Med (Lausanne)
. 2019 Sep;
6:179.
PMID: 31555647
The insulin-like growth factor 2 () mRNA binding proteins (IMPs/IGF2BPs) IMP1 and 3 are regarded as oncofetal proteins, whereas the hepatic IMP2 expression in adults is controversially discussed. The splice...
17.
Starkel P, Schnabl B, Leclercq S, Komuta M, Bataller R, Argemi J, et al.
Hepatol Commun
. 2019 Jul;
3(7):867-882.
PMID: 31334440
Mechanisms underlying alcohol-induced liver injury and its progression still remain incompletely understood. Animal models can only address some aspects of the pathophysiology that requires studies directly in humans, which are...
18.
Manco R, Clerbaux L, Verhulst S, Bou Nader M, Sempoux C, Ambroise J, et al.
J Hepatol
. 2019 Feb;
70(6):1180-1191.
PMID: 30794890
Background & Aim: Chronic liver diseases are characterized by expansion of the small immature cholangiocytes - a mechanism named ductular reaction (DR) - which have the capacity to differentiate into...
19.
Van Dievoet M, Leclercq I, Hermans C, Lambert C, Horsmans Y, Jacquemin M, et al.
Haemophilia
. 2018 Nov;
25(1):e32-e35.
PMID: 30427101
No abstract available.
20.
Farrell G, Schattenberg J, Leclercq I, Yeh M, Goldin R, Teoh N, et al.
Hepatology
. 2018 Oct;
69(5):2241-2257.
PMID: 30372785
Nonalcoholic steatohepatitis (NASH) arises from a variable interplay between environmental factors and genetic determinants that cannot be completely replicated in animals. Notwithstanding, preclinical models are needed to understand NASH pathophysiology...