Isabelle Lahaie
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Explore the profile of Isabelle Lahaie including associated specialties, affiliations and a list of published articles.
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21
Citations
302
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Recent Articles
1.
Nazari A, Gresseau L, Habelrih T, Zia A, Lahaie I, Er-Reguyeg Y, et al.
Biomedicines
. 2025 Jan;
12(12.
PMID: 39767576
Choroidal involution is a common feature of age-related ischemic retinopathies such as age-related macular degeneration (AMD). It is now well recognized that endothelial progenitor cells (EPCs) are essential to endothelial...
2.
Meunier E, Aubin Vega M, Adam D, Prive A, Mohammad Nezhady M, Lahaie I, et al.
Exp Physiol
. 2024 Apr;
109(6):966-979.
PMID: 38594909
The acute exudative phase of acute respiratory distress syndrome (ARDS), a severe form of respiratory failure, is characterized by alveolar damage, pulmonary oedema, and an exacerbated inflammatory response. There is...
3.
Ruknudin P, Nazari A, Wirth M, Lahaie I, Bajon E, Rivard A, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685993
Endothelial Progenitor Cells (EPCs) can actively participate in revascularization in oxygen-induced retinopathy (OIR). Yet the mechanisms responsible for their dysfunction is unclear. Nogo-A, whose function is traditionally related to the...
4.
Desjarlais M, Ruknudin P, Wirth M, Lahaie I, Dabouz R, Rivera J, et al.
Front Cell Dev Biol
. 2021 Jun;
9:679906.
PMID: 34124069
Background And Aim: Insufficient post-ischemic neovascularization is an initial key step in the pathogenesis of Oxygen-Induced Retinopathy (OIR). During neovascularization, pro-angiogenic cells (PACs) are mobilized from the bone marrow and...
5.
Noueihed B, Rivera J, Dabouz R, Abram P, Omri S, Lahaie I, et al.
Front Cell Dev Biol
. 2021 Feb;
9:630645.
PMID: 33553187
Ischemic retinopathies (IRs), such as retinopathy of prematurity and diabetic retinopathy, are characterized by an initial phase of microvascular degeneration that results in retinal ischemia, followed by exaggerated pathologic neovascularization...
6.
Geranurimi A, Cheng C, Quiniou C, Cote F, Hou X, Lahaie I, et al.
Front Chem
. 2021 Jan;
8:610431.
PMID: 33415098
As a key cytokine mediator of inflammation, interleukin-1β (IL-1β) binds to the IL-1 receptor (IL-1R) and activates various downstream signaling mediators, including NF-κB, which is required for immune vigilance and...
7.
Desjarlais M, Wirth M, Lahaie I, Ruknudin P, Hardy P, Rivard A, et al.
Front Pharmacol
. 2020 Dec;
11:602999.
PMID: 33362557
The coronavirus disease 2019 (COVID-19) pandemic has become the number one health problem worldwide. As of August 2020, it has affected more than 18 million humans and caused over 700,000...
8.
Desjarlais M, Wirth M, Rivera J, Lahaie I, Dabouz R, Omri S, et al.
Front Pharmacol
. 2020 Mar;
11:13.
PMID: 32116694
Background And Aims: Vascular degeneration is a hallmark in the pathogenesis of oxygen-induced retinopathy (OIR). Dysregulation of microRNAs (miRNAs), key regulators of genes expressions, has been implicated in the regulation...
9.
Omri S, Tahiri H, Pierre W, Desjarlais M, Lahaie I, Loiselle S, et al.
Invest Ophthalmol Vis Sci
. 2019 Nov;
60(14):4632-4642.
PMID: 31682714
Purpose: Targeting β-adrenergic receptor signaling with propranolol has emerged as a potential candidate to counteract choroidal neovascularization (CNV). Little is known of its effect on macrophages, which play a critical...
10.
Zhou T, Zhu T, Rivera J, Omri S, Tahiri H, Lahaie I, et al.
Am J Pathol
. 2019 Aug;
189(11):2340-2356.
PMID: 31430465
Retinopathy of prematurity (ROP) is characterized by an initial retinal avascularization, followed by pathologic neovascularization. Recently, choroidal thinning has also been detected in children formerly diagnosed with ROP; a similar...