Isabelle Gennero
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Explore the profile of Isabelle Gennero including associated specialties, affiliations and a list of published articles.
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32
Citations
474
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Recent Articles
1.
Ballout N, Toumieux S, Darwiche W, Gomila C, Trecherel E, Accadbled F, et al.
Pharmaceuticals (Basel)
. 2025 Feb;
18(2).
PMID: 40006029
: Delays in bone healing and complications of remodeling constitute a major medical problem-particularly in older adults and patients with comorbidities. Current therapeutic approaches are based on strategies that promote...
2.
Briand-Mesange F, Gennero I, Salles J, Trudel S, Dahan L, Ausseil J, et al.
Molecules
. 2024 Aug;
29(15).
PMID: 39125098
2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the...
3.
Salles J, Eddiry S, Amri S, Galindo M, Lacassagne E, George S, et al.
Mol Psychiatry
. 2024 Apr;
29(9):2742-2752.
PMID: 38561465
Introduction: A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) features. PWS is a neurodevelopmental disorder clinically characterized by endocrine impairment, intellectual...
4.
Ballout N, Boullier A, Darwiche W, Ait-Mohand K, Trecherel E, Gallego T, et al.
Pharmaceuticals (Basel)
. 2023 Nov;
16(11).
PMID: 38004380
Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony callus formation, and bone remodelling. Bone fractures represent a significant...
5.
Rouleau C, Malorie M, Collet C, Porquet-Bordes V, Gennero I, Eddiry S, et al.
Bone Rep
. 2022 Mar;
16:101176.
PMID: 35252483
Aim: To describe the presenting features, bone characteristics and molecular genetics in a large monocentric cohort of children and young adults with idiopathic primary osteoporosis. Methods: Sixty-six patients (19 children,...
6.
Pacoricona Alfaro D, Diene G, Pinto G, Salles J, Gennero I, Faye S, et al.
Orphanet J Rare Dis
. 2021 Jul;
16(1):305.
PMID: 34238321
Background: Adolescents with idiopathic scoliosis display high ghrelin levels. As hyperghrelinemia is found in patients with PWS and early-onset scoliosis (EOS) is highly prevalent in these patients, our aims were...
7.
Eddiry S, Diene G, Molinas C, Salles J, Auriol F, Gennero I, et al.
Genet Med
. 2021 May;
23(9):1664-1672.
PMID: 34040195
Purpose: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the 15q11-q13 chromosome. Among them, the SNORD116 gene appears critical for...
8.
Ostkamp P, Salmen A, Pignolet B, Gorlich D, Andlauer T, Schulte-Mecklenbeck A, et al.
Proc Natl Acad Sci U S A
. 2020 Dec;
118(1).
PMID: 33376202
Multiple sclerosis (MS) disease risk is associated with reduced sun-exposure. This study assessed the relationship between measures of sun exposure (vitamin D [vitD], latitude) and MS severity in the setting...
9.
Barre R, Beton N, Batut A, Accabled F, Sales de Gauzy J, Auriol F, et al.
Biochem Biophys Rep
. 2020 Sep;
24:100782.
PMID: 32984555
We have examined the Acylated Ghrelin (AG)/Gi pathway in different human osteoblastic cell lines. We have found that: 1) AG induces differentiation/mineralization only in mature osteoblasts; 2) the expression of...
10.
HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment
Mascarau R, Bertrand F, Labrousse A, Gennero I, Poincloux R, Maridonneau-Parini I, et al.
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32365752
HIV-1 infection is frequently associated with low bone density, which can progress to osteoporosis leading to a high risk of fractures. Only a few mechanisms have been proposed to explain...