Alpha 2.0
Login Register
» Authors » Isabelle Daigle

Isabelle Daigle

Explore the profile of Isabelle Daigle including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 241
Followers 0
Related Specialties
Biology
Allergy & Immunology
General Medicine
Top 10 Co-Authors
Hans-Uwe Simon
Kurt Blaser
Cezmi A Akdis
Mubeccel Akdis
Marco Colonna
Renate Wenig
Francesca Levi-Schaffer
Axel Trautmann
Jason Lieberthal
Chris Li
Published In
Nat Med
Dermatology
J Allergy Clin Immunol
Pediatr Res
J Immunol
Affiliations
Soon will be listed here.
Recent Articles
1.
IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1
Taylor A, Akdis M, Joss A, Akkoc T, Wenig R, Colonna M, et al.
J Allergy Clin Immunol . 2007 May; 120(1):76-83. PMID: 17531298
Background: Specific T-cell activation requires T-cell receptor stimulation and the generation of costimulatory signals. Major costimulatory signals are delivered to T cells by the interaction of CD28 and inducible costimulator...
2.
APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability
Hornsten A, Lieberthal J, Fadia S, Malins R, Ha L, Xu X, et al.
Proc Natl Acad Sci U S A . 2007 Feb; 104(6):1971-6. PMID: 17267616
Dominant mutations in the amyloid precursor protein (APP) gene are associated with rare cases of familial Alzheimer's disease; however, the normal functions of APP and related proteins remain unclear. The...
3.
Human mast cells undergo TRAIL-induced apoptosis
Berent-Maoz B, Piliponsky A, Daigle I, Simon H, Levi-Schaffer F
J Immunol . 2006 Feb; 176(4):2272-8. PMID: 16455983
Mast cells (MC), supposedly long-lived cells, play a key role in allergy and are important contributors to other inflammatory conditions in which they undergo hyperplasia. In humans, stem cell factor...
4.
Fas ligand reduces viability in primary melanoma short-term cell cultures more than in metastatic melanoma short-term cell cultures
Hofbauer G, Hatta N, Daigle I, Hemmi S, Spanaus Schlapbach K, Willers J, et al.
Dermatology . 2005 Nov; 211(4):318-24. PMID: 16286739
Background: Apoptotic pathway aberrations are reported as important tumor progression factors in melanoma. Objective: Effect of soluble Fas ligand (sFasL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) on short-term cultured...
5.
T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells
Akdis M, Trautmann A, Klunker S, Daigle I, Kucuksezer U, Deglmann W, et al.
FASEB J . 2003 May; 17(9):1026-35. PMID: 12773485
T cells constitute a large population of cellular infiltrate in atopic/allergic inflammation and a dysregulated, Th2-biased peripheral immune response appears to be an important pathogenetic factor. In atopic dermatitis, circulating...
6.
IL-10 controls Aspergillus fumigatus- and Pseudomonas aeruginosa-specific T-cell response in cystic fibrosis
Casaulta C, Schoni M, Weichel M, Crameri R, Jutel M, Daigle I, et al.
Pediatr Res . 2003 Jan; 53(2):313-9. PMID: 12538792
Up to 90% of patients with cystic fibrosis (CF) are chronically colonized with Pseudomonas aeruginosa, and 10% to 50% of CF patients are colonized with Aspergillus fumigatus. Despite an extensive...
7.
Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils
Daigle I, Yousefi S, Colonna M, Green D, Simon H
Nat Med . 2002 Jan; 8(1):61-7. PMID: 11786908
Death domain-containing receptors of the tumor necrosis factor (TNF)/nerve growth factor (NGF) family can induce apoptosis upon activation in many cellular systems. We show here that a conserved phosphotyrosine-containing motif...