Isabella Rusciano
Overview
Explore the profile of Isabella Rusciano including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
137
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0
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Recent Articles
1.
Koufi F, Neri I, Ramazzotti G, Rusciano I, Mongiorgi S, Marvi M, et al.
Front Cell Neurosci
. 2023 Sep;
17:1263310.
PMID: 37720548
Lamin B1 is an essential protein of the nuclear lamina that plays a crucial role in nuclear function and organization. It has been demonstrated that lamin B1 is essential for...
2.
Neri I, Ramazzotti G, Mongiorgi S, Rusciano I, Bugiani M, Conti L, et al.
Mol Neurobiol
. 2023 Jul;
60(11):6362-6372.
PMID: 37450245
Autosomal dominant leukodystrophy (ADLD) is an ultra-rare, slowly progressive, and fatal neurodegenerative disorder associated with the loss of white matter in the central nervous system (CNS). Several years after its...
3.
De Stefano A, Rusciano I, Moretti V, Scavarda A, Green M, Wall S, et al.
Anat Sci Educ
. 2022 Nov;
16(2):209-223.
PMID: 36346170
Cadaver dissection has always played a fundamental role in medical education. However, especially in Italy, the topic of body donation has remained partially unknown for years. The current study analyses...
4.
Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness
Ratti S, Marvi M, Mongiorgi S, Obeng E, Rusciano I, Ramazzotti G, et al.
Cell Mol Life Sci
. 2022 Mar;
79(4):195.
PMID: 35303162
Glioblastoma represents the most lethal brain tumor in adults. Several studies have shown the key role of phospholipase C β1 (PLCβ1) in the regulation of many mechanisms within the central...
5.
Evangelisti C, Rusciano I, Mongiorgi S, Ramazzotti G, Lattanzi G, Manzoli L, et al.
Cell Mol Life Sci
. 2022 Feb;
79(2):126.
PMID: 35132494
B-type lamins are fundamental components of the nuclear lamina, a complex structure that acts as a scaffold for organization and function of the nucleus. Lamin B1 and B2, the most...
6.
Ratti S, Rusciano I, Mongiorgi S, Neri I, Cappellini A, Cortelli P, et al.
Cells
. 2021 Oct;
10(10).
PMID: 34685544
Autosomal dominant leukodystrophy (ADLD) is an extremely rare and fatal neurodegenerative disease due to the overexpression of the nuclear lamina component Lamin B1. Many aspects of the pathology still remain...
7.
Rusciano I, Marvi M, Obeng E, Mongiorgi S, Ramazzotti G, Follo M, et al.
Adv Biol Regul
. 2020 Dec;
79:100771.
PMID: 33303387
Phosphoinositide-specific phospholipases C (PI-PLCs) are a class of enzymes involved in the phosphatidylinositol metabolism, which is implicated in the activation of several signaling pathways and which controls several cellular processes....
8.
Ratti S, Rusciano I, Mongiorgi S, Obeng E, Cappellini A, Teti G, et al.
Cell Mol Life Sci
. 2020 Oct;
78(6):2781-2795.
PMID: 33034697
Autosomal-dominant leukodystrophy (ADLD) is a rare fatal neurodegenerative disorder with overexpression of the nuclear lamina component, Lamin B1 due to LMNB1 gene duplication or deletions upstream of the gene. The...
9.
Fazio A, Obeng E, Rusciano I, Marvi M, Zoli M, Mongiorgi S, et al.
Int J Mol Sci
. 2020 Jul;
21(15).
PMID: 32722576
An increasing number of reports suggests a significant involvement of the phosphoinositide (PI) cycle in cancer development and progression. Diacylglycerol kinases (DGKs) are very active in the PI cycle. They...
10.
Poli A, Fiume R, Mongiorgi S, Zaurito A, Sheth B, Vidalle M, et al.
Adv Biol Regul
. 2020 May;
76:100722.
PMID: 32362560
The immune system is a complex network that acts to protect vertebrates from foreign microorganisms and carries out immunosurveillance to combat cancer. In order to avoid hyper-activation of the immune...