Isabella M Bray
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Explore the profile of Isabella M Bray including associated specialties, affiliations and a list of published articles.
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11
Citations
532
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Recent Articles
1.
Lynch J, Meehan M, Crean J, Copeland J, Stallings R, Bray I
PLoS One
. 2023 Dec;
18(12):e0295370.
PMID: 38096183
[This corrects the article DOI: 10.1371/journal.pone.0078428.].
2.
Miller-Delaney S, Bryan K, Das S, McKiernan R, Bray I, Reynolds J, et al.
Brain
. 2015 Jan;
138(Pt 3):616-31.
PMID: 25552301
Temporal lobe epilepsy is associated with large-scale, wide-ranging changes in gene expression in the hippocampus. Epigenetic changes to DNA are attractive mechanisms to explain the sustained hyperexcitability of chronic epilepsy....
3.
Harvey H, Piskareva O, Creevey L, Alcock L, Buckley P, OSullivan M, et al.
Int J Cancer
. 2014 Aug;
136(7):1579-88.
PMID: 25137037
The acquisition of multidrug resistance is a major impediment to the successful treatment of neuroblastoma, a clinically heterogeneous cancer accounting for ∼15% of all pediatric cancer deaths. The MYCN transcription...
4.
Bryan K, Terrile M, Bray I, Domingo-Fernandez R, Watters K, Koster J, et al.
Nucleic Acids Res
. 2013 Dec;
42(3):e17.
PMID: 24357407
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at a post-transcriptional level. An miRNA may target many messenger RNA (mRNA) transcripts, and each transcript may be targeted...
5.
Lynch J, Meehan M, Crean J, Copeland J, Stallings R, Bray I
PLoS One
. 2013 Nov;
8(11):e78428.
PMID: 24223803
MiRNAs can have pleiotropic effects by targeting multiple genes belonging to diverse signalling networks. Alternatively, miRNAs can enhance the potency of their cellular effects by targeting multiple genes within the...
6.
Creevey L, Ryan J, Harvey H, Bray I, Meehan M, Khan A, et al.
Mol Cancer
. 2013 Mar;
12:23.
PMID: 23531080
Background: Neuroblastoma is responsible for 15% of all childhood cancer deaths. Despite advances in treatment and disease management, the overall 5-year survival rates remain poor in high-risk disease (25-40%). MiR-497...
7.
Althoff K, Beckers A, Odersky A, Mestdagh P, Koster J, Bray I, et al.
Int J Cancer
. 2013 Feb;
133(5):1064-73.
PMID: 23400681
Neuroblastoma is the most common extracranial solid tumor of childhood, and accounts for ∼15% of all childhood cancer deaths. The histone demethylase, lysine-specific demethylase 1 (KDM1A, previously known as LSD1),...
8.
Tivnan A, Orr W, Gubala V, Nooney R, Williams D, McDonagh C, et al.
PLoS One
. 2012 Jun;
7(5):e38129.
PMID: 22662276
Background: Neuroblastoma is one of the most challenging malignancies of childhood, being associated with the highest death rate in paediatric oncology, underlining the need for novel therapeutic approaches. Typically, patients...
9.
Stallings R, Foley N, Bray I, Das S, Buckley P
Semin Cancer Biol
. 2011 Jul;
21(4):283-90.
PMID: 21771658
Many neuroblastoma cell lines can be induced to differentiate into a mature neuronal cell type with retinoic acid and other compounds, providing an important model system for elucidating signalling pathways...
10.
MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2
Foley N, Bray I, Tivnan A, Bryan K, Murphy D, Buckley P, et al.
Mol Cancer
. 2010 Apr;
9:83.
PMID: 20409325
Background: Neuroblastoma is a paediatric cancer of the sympathetic nervous system. The single most important genetic indicator of poor clinical outcome is amplification of the MYCN transcription factor. One of...