Isabel Klugherz
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Explore the profile of Isabel Klugherz including associated specialties, affiliations and a list of published articles.
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6
Citations
54
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Recent Articles
1.
Schub T, Klugherz I, Wagener J, Prattes J, Hoenigl M, Suerbaum S, et al.
J Clin Microbiol
. 2024 Nov;
62(12):e0095024.
PMID: 39494863
Invasive aspergillosis (IA) is a life-threatening infection. Early and specific diagnosis is pivotal to ensure adequate therapy. Antigen testing from blood is a widespread and convenient diagnostic approach. Various tests...
2.
Elsaman H, Golubtsov E, Brazil S, Ng N, Klugherz I, Martin R, et al.
Nat Commun
. 2024 Jul;
15(1):6312.
PMID: 39060235
Azole antifungals inhibit the sterol C14-demethylase (CYP51/Erg11) of the ergosterol biosynthesis pathway. Here we show that the azole-induced synthesis of fungicidal cell wall carbohydrate patches in the pathogenic mold Aspergillus...
3.
Bhattarai S, Klugherz I, Mukhopadhyay C, Steinmetz I
IJID Reg
. 2024 Jun;
11:100377.
PMID: 38872919
Melioidosis, an emerging infectious disease caused by the Gram-negative bacillus , is massively underdiagnosed in many low- and middle-income countries. The disease is clinically extremely variable, has a high case...
4.
Klugherz I, Basch M, Ng N, Zhu Z, Wagener N, Wagener J
J Fungi (Basel)
. 2023 Nov;
9(11).
PMID: 37998879
The mitochondrial translocase Bcs1 is required for the correct assembly of complex III of the mitochondrial respiratory chain. Because of its importance, Bcs1 was recently proposed as a target for...
5.
A head-to-head comparison of three MALDI-TOF mass spectrometry systems with 16S rRNA gene sequencing
Dichtl K, Klugherz I, Greimel H, Luxner J, Koberl J, Friedl S, et al.
J Clin Microbiol
. 2023 Sep;
61(10):e0191322.
PMID: 37732759
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized diagnostics in culture-based microbiology. Commonly used MALDI-TOF MS systems in clinical microbiology laboratories are MALDI Biotyper (Bruker Daltonics) and Vitek...
6.
Geissel B, Loiko V, Klugherz I, Zhu Z, Wagener N, Kurzai O, et al.
Nat Commun
. 2018 Aug;
9(1):3098.
PMID: 30082817
Azole antifungals inhibit the fungal ergosterol biosynthesis pathway, resulting in either growth inhibition or killing of the pathogen, depending on the species. Here we report that azoles have an initial...