Isabel Delany
Overview
Explore the profile of Isabel Delany including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
1486
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Recent Articles
1.
Ariolli A, Cane M, Di Fede M, Tavarini S, Taddei A, Buno K, et al.
Front Cell Infect Microbiol
. 2024 May;
14:1397940.
PMID: 38751999
Non-typeable (NTHi) and (Mcat) are two common respiratory tract pathogens often associated with acute exacerbations in Chronic Obstructive Pulmonary Disease (COPD) as well as with otitis media (OM) in children....
2.
Viviani V, Fantoni A, Tomei S, Marchi S, Luzzi E, Bodini M, et al.
NPJ Vaccines
. 2023 Apr;
8(1):54.
PMID: 37045859
The ability of Neisseria meningitidis Outer Membrane Vesicles (OMV) to induce protective responses in humans is well established and mainly attributed to Porin A (PorA). However, the contribution of additional...
3.
Haag A, Liljeroos L, Donato P, Pozzi C, Brignoli T, Bottomley M, et al.
Microbiol Spectr
. 2023 Jan;
11(1):e0257422.
PMID: 36688711
Staphylococcus aureus is a clinically important bacterial pathogen that has become resistant to treatment with most routinely used antibiotics. Alternative strategies, such as vaccination and phage therapy, are therefore actively...
4.
Alfini R, Brunelli B, Bartolini E, Carducci M, Luzzi E, Ferlicca F, et al.
Vaccines (Basel)
. 2022 Jul;
10(8).
PMID: 35893831
GMMA are outer membrane vesicles (OMVs) released from Gram-negative bacteria genetically modified to enhance OMVs formation that have been shown to be optimal systems to enhance immunogenicity of protein antigens....
5.
Borghi S, Antunes A, Haag A, Spinsanti M, Brignoli T, Ndoni E, et al.
Microorganisms
. 2022 Apr;
10(4).
PMID: 35456883
Neisseria meningitidis colonizes the nasopharynx of humans, and pathogenic strains can disseminate into the bloodstream, causing septicemia and meningitis. NHBA is a surface-exposed lipoprotein expressed by all N. meningitidis strains...
6.
Nicchi S, Giusti F, Carello S, Utrio Lanfaloni S, Tavarini S, Frigimelica E, et al.
iScience
. 2022 Mar;
25(3):103931.
PMID: 35265810
and nontypeable (NTHi) are pathogenic bacteria frequently associated with exacerbation of chronic obstructive pulmonary disease (COPD), whose hallmark is inflammatory oxidative stress. Neutrophils produce reactive oxygen species (ROS) which can...
7.
Antonelli G, Cappelli L, Cinelli P, Cuffaro R, Manca B, Nicchi S, et al.
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34066555
Traditional antimicrobial treatments consist of drugs which target different essential functions in pathogens. Nevertheless, bacteria continue to evolve new mechanisms to evade this drug-mediated killing with surprising speed on the...
8.
Spinsanti M, Brignoli T, Bodini M, Fontana L, De Chiara M, Biolchi A, et al.
PLoS Pathog
. 2021 Mar;
17(3):e1009461.
PMID: 33770146
Neisseria meningitidis is a strictly human pathogen and is the major cause of septicemia and meningitis worldwide. Factor H binding protein (fHbp) is a meningococcal surface-exposed lipoprotein that binds the...
9.
Nicchi S, Giuliani M, Giusti F, Pancotto L, Maione D, Delany I, et al.
Microb Cell Fact
. 2021 Feb;
20(1):33.
PMID: 33531008
Background: The display of recombinant proteins on cell surfaces has a plethora of applications including vaccine development, screening of peptide libraries, whole-cell biocatalysts and biosensor development for diagnostic, industrial or...
10.
Seib K, Haag A, Oriente F, Fantappie L, Borghi S, Semchenko E, et al.
FASEB J
. 2019 Aug;
33(11):12324-12335.
PMID: 31442078
GNA2091 is one of the components of the 4-component meningococcal serogroup B vaccine (4CMenB) vaccine and is highly conserved in all meningococcal strains. However, its functional role has not been...