Irute Girkontaite
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Explore the profile of Irute Girkontaite including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
390
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Recent Articles
1.
Baleviciute A, Radzeviciute E, Zelvys A, Malysko-Ptasinske V, Novickij J, Zinkeviciene A, et al.
Cancers (Basel)
. 2022 Dec;
14(24).
PMID: 36551739
In this work, a time-dependent and time-independent study on bleomycin-based high-frequency nsECT (3.5 kV/cm × 200 pulses) for the elimination of LLC1 tumours in C57BL/6J mice is performed. We show...
2.
Radzeviciute E, Malysko-Ptasinske V, Kulbacka J, Rembialkowska N, Novickij J, Girkontaite I, et al.
Bioelectrochemistry
. 2022 Sep;
148:108251.
PMID: 36049422
Electroporation is a pulsed electric field (PEF) induced phenomenon, which effectiveness varies dependent on pulse parameters. This work focuses on nano-electrochemotherapy with bleomycin and doxorubicin to derive protocols as effective...
3.
Ruzgys P, Navickaite D, Palepsiene R, Uzdavinyte D, Barauskaite N, Novickij V, et al.
Cancers (Basel)
. 2022 Aug;
14(15).
PMID: 35954434
Electroporation-based antitumor therapies, including bleomycin electrotransfer, calcium electroporation, and irreversible electroporation, are very effective on directly treated tumors, but have no or low effect on distal nodules. In this study,...
4.
Radzeviciute E, Malysko-Ptasinske V, Novickij J, Novickij V, Girkontaite I
Pharmaceutics
. 2022 Jun;
14(6).
PMID: 35745814
Gene transfer into primary immune cells as well as into cell lines is essential for scientific and therapeutical applications. One of the methods used for gene transfer is electroporation (EP)....
5.
Novickij V, Zinkeviciene A, Radzeviciute E, Kulbacka J, Rembialkowska N, Novickij J, et al.
Bioelectrochemistry
. 2022 Feb;
145:108084.
PMID: 35144166
Electroporation is a phenomenon of transient or irreversible permeabilization of the cell membrane after pulsed electric field treatment. Fluorescent probes are frequently used to assess the extent of permeabilization, however,...
6.
Novickij V, Baleviciute A, Malysko V, Zelvys A, Radzeviciute E, Kos B, et al.
IEEE Trans Biomed Eng
. 2021 Nov;
69(5):1726-1732.
PMID: 34797759
Objective: this work focuses on bleomycin electrochemotherapy using new modality of high repetition frequency unipolar nanosecond pulses. Methods: As a tumor model, Lewis lung carcinoma (LLC1) cell line in C57BL...
7.
Kulbacka J, Rembialkowska N, Szewczyk A, Moreira H, Szyjka A, Girkontaite I, et al.
Cancers (Basel)
. 2021 Jul;
13(13).
PMID: 34203184
(1) Background: Calcium electroporation (CaEP) is based on the application of electrical pulses to permeabilize cells (electroporation) and allow cytotoxic doses of calcium to enter the cell. (2) Methods: In...
8.
Novickij V, Zinkeviciene A, Malysko V, Novickij J, Kulbacka J, Rembialkowska N, et al.
J Photochem Photobiol B
. 2020 Nov;
213:112066.
PMID: 33142215
The cell membrane permeabilization in electroporation studies is usually quantified using fluorescent markers such as propidium iodide (PI) or YO-PRO, while Chinese Hamster Ovary cell line frequently serves as a...
9.
Novickij V, Malysko V, Zelvys A, Baleviciute A, Zinkeviciene A, Novickij J, et al.
Molecules
. 2020 Oct;
25(20).
PMID: 33050300
Pulsed electric field (PEF) is frequently used for intertumoral drug delivery resulting in a well-known anticancer treatment-electrochemotherapy. However, electrochemotherapy is associated with microsecond range of electrical pulses, while nanosecond range...
10.
Novickij V, Baleviciute A, Ruzgys P, Satkauskas S, Novickij J, Zinkeviciene A, et al.
Bioelectrochemistry
. 2020 Jul;
136:107594.
PMID: 32679337
Micro-millisecond range electric field pulses have been used for decades to facilitate DNA transfer into cells and tissues, while the growing number of clinical trials underline the strong potential of...