Iris Poh Ling Wong
Overview
Explore the profile of Iris Poh Ling Wong including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
9
Followers
0
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Recent Articles
1.
Cheung B, Mittra R, Murray J, Wang Q, Seneviratne J, Raipuria M, et al.
Commun Biol
. 2024 Oct;
7(1):1322.
PMID: 39402275
MYCN amplification predicts poor prognosis in childhood neuroblastoma. To identify MYCN oncogenic signal dependencies we performed N-ethyl-N-nitrosourea (ENU) mutagenesis on the germline of neuroblastoma-prone TH-MYCN transgenic mice to generate founders...
2.
Cheung B, Kleynhans A, Mittra R, Kim P, Holien J, Nagy Z, et al.
Oncogene
. 2021 Mar;
40(13):2367-2381.
PMID: 33658627
Histone deacetylase (HDAC) inhibitors are effective in MYCN-driven cancers, because of a unique need for HDAC recruitment by the MYCN oncogenic signal. However, HDAC inhibitors are much more effective in...