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Irina Surovtsova

Explore the profile of Irina Surovtsova including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 47
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Recent Articles
1.
Surovtsova I, Herth F, Kokh D, Morakis P
Pulmonology . 2025 Feb; 31(1):2457856. PMID: 39907049
Background: Pembrolizumab with chemotherapy (immunochemotherapy) has shown encouraging overall survival (OS) benefits in non-squamous mNSCLC, as demonstrated by the KEYNOTE-189 trial. However, randomised controlled trials may not fully capture the...
2.
Schuhbaur J, Surovtsova I, Seufferlein T, Kokh D, Szotyori-Artz G, Winzler C, et al.
BMC Cancer . 2024 Oct; 24(1):1280. PMID: 39407151
Background: Ductal pancreatic adenocarcinoma (PDAC) still has a dismal prognosis even when deemed resectable. A cancer free resection margin (R0) is associated with a more favourable prognosis than the presence...
3.
Pfob A, Surovtsova I, Kokh D, Heil J, Banys-Paluchowski M, Morakis P
Int J Cancer . 2024 Sep; 156(3):587-597. PMID: 39291633
We aimed to evaluate the role of adjuvant chemotherapy and loco-regional therapy for stage IA (pT1, pN0) triple-negative breast cancer (TNBC) in a real-world setting. We identified patients with pT1,...
4.
Pfob A, Kokh D, Surovtsova I, Riedel F, Morakis P, Heil J
Ann Surg Oncol . 2024 May; 31(7):4381-4392. PMID: 38710911
Background: Targeted approaches such as targeted axillary dissection (TAD) or sentinel lymph node biopsy (SLNB) showed false-negative rates of < 10% compared with axillary lymph node dissection (ALND) in patients...
5.
Worst T, Surovtsova I, Vogel T, Zauser M, Neuberger M, Wessels F, et al.
Urologie . 2024 Feb; 63(7):681-692. PMID: 38316650
Background: Prostate cancer (PCa) is the most common solid tumor in men in Germany. Collection of epidemiological and clinical data has been centralized for several years due to legal requirements...
6.
Teufel A, Rodriguez I, Winzler C, Kokh D, Ebert M, Surovtsova I, et al.
J Gastrointestin Liver Dis . 2023 Jun; 32(2):190-196. PMID: 37345609
Background And Aims: Primary liver cancer (PLC) ranks among of the most common cancers worldwide. Within this group, a minority of cases displays characteristics of both hepatocellular carcinoma (HCC) and...
7.
Hubner K, Surovtsova I, Yserentant K, Hansch M, Kummer U
Biophys Chem . 2013 Nov; 184:116-25. PMID: 24262430
Central to the immune defense function of neutrophils is to sense, to move and to kill. Neutrophils acquire distinct cellular states necessary to fulfill these functions each associated with a...
8.
Surovtsova I, Simus N, Hubner K, Sahle S, Kummer U
BMC Syst Biol . 2012 Mar; 6:14. PMID: 22390191
Background: Given the complex mechanisms underlying biochemical processes systems biology researchers tend to build ever increasing computational models. However, dealing with complex systems entails a variety of problems, e.g. difficult...
9.
Surovtsova I, Simus N, Lorenz T, Konig A, Sahle S, Kummer U
Bioinformatics . 2009 Jul; 25(21):2816-23. PMID: 19633098
Motivation: The growing complexity of biochemical models asks for means to rationally dissect the networks into meaningful and rather independent subnetworks. Such foregoing should ensure an understanding of the system...
10.
Weidemann A, Richter S, Stein M, Sahle S, Gauges R, Gabdoulline R, et al.
Bioinformatics . 2008 May; 24(12):1463-4. PMID: 18463116
Unlabelled: SYCAMORE is a browser-based application that facilitates construction, simulation and analysis of kinetic models in systems biology. Thus, it allows e.g. database supported modelling, basic model checking and the...