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Ireneusz Litwin

Explore the profile of Ireneusz Litwin including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 175
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Recent Articles
1.
Wysocki R, Rodrigues J, Litwin I, Tamas M
Cell Mol Life Sci . 2023 Oct; 80(11):342. PMID: 37904059
Arsenic and antimony are metalloids with profound effects on biological systems and human health. Both elements are toxic to cells and organisms, and exposure is associated with several pathological conditions...
2.
Litwin I, Nowicka M, Markowska K, Maciaszczyk-Dziubinska E, Tomaszewska P, Wysocki R, et al.
Nucleic Acids Res . 2023 Jul; 51(17):9101-9121. PMID: 37486771
Cohesin is a highly conserved, multiprotein complex whose canonical function is to hold sister chromatids together to ensure accurate chromosome segregation. Cohesin association with chromatin relies on the Scc2-Scc4 cohesin...
3.
Kedziora A, Wieczorek R, Speruda M, Matolinova I, Goszczynski T, Litwin I, et al.
Front Microbiol . 2021 Jul; 12:659614. PMID: 34276595
The aim of this study was to compare the antibacterial mode of action of silver ions (Ag) and selected silver nanoformulations against strains ( J53, BW25113 and its derivatives: Δ...
4.
Litwin I, Mucha S, Pilarczyk E, Wysocki R, Maciaszczyk-Dziubinska E
Int J Mol Sci . 2021 Apr; 22(9). PMID: 33925940
Antimony is a toxic metalloid with poorly understood mechanisms of toxicity and uncertain carcinogenic properties. By using a combination of genetic, biochemical and DNA damage assays, we investigated the genotoxic...
5.
Cal M, Matyjaszczyk I, Litwin I, Augustyniak D, Ogorek R, Ko Y, et al.
Cells . 2020 May; 9(5). PMID: 32397119
3-bromopyruvate (3-BP) is a small molecule with anticancer and antimicrobial activities. 3-BP is taken up selectively by cancer cells' mono-carboxylate transporters (MCTs), which are highly overexpressed by many cancers. When...
6.
Litwin I, Pilarczyk E, Wysocki R
Genes (Basel) . 2018 Nov; 9(12). PMID: 30487431
Faithful transmission of genetic material is crucial for all organisms since changes in genetic information may result in genomic instability that causes developmental disorders and cancers. Thus, understanding the mechanisms...
7.
Litwin I, Bakowski T, Szakal B, Pilarczyk E, Maciaszczyk-Dziubinska E, Branzei D, et al.
EMBO J . 2018 Aug; 37(18). PMID: 30111537
DNA damage tolerance (DDT) mechanisms facilitate replication resumption and completion when DNA replication is blocked by bulky DNA lesions. In budding yeast, template switching (TS) via the Rad18/Rad5 pathway is...
8.
Litwin I, Wysocki R
Curr Genet . 2017 Jun; 64(1):53-61. PMID: 28631016
Cohesin is a conserved, ring-shaped protein complex that encircles sister chromatids and ensures correct chromosome segregation during mitosis and meiosis. It also plays a crucial role in the regulation of...
9.
Litwin I, Bakowski T, Maciaszczyk-Dziubinska E, Wysocki R
Nucleic Acids Res . 2017 Apr; 45(11):6404-6416. PMID: 28383696
Accurate chromosome segregation is essential for every living cell as unequal distribution of chromosomes during cell division may result in genome instability that manifests in carcinogenesis and developmental disorders. Irc5...
10.
Kramarz K, Mucha S, Litwin I, Barg-Wojas A, Wysocki R, Dziadkowiec D
Genetics . 2017 Mar; 206(1):513-525. PMID: 28341648
DNA damage tolerance and homologous recombination pathways function to bypass replication-blocking lesions and ensure completion of DNA replication. However, inappropriate activation of these pathways may lead to increased mutagenesis or...