Irene Nicolas
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Explore the profile of Irene Nicolas including associated specialties, affiliations and a list of published articles.
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6
Citations
59
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Recent Articles
1.
Fermon L, Germain-Amiot N, Oriol C, Rouillon A, Augagneur Y, Dreano S, et al.
FEBS J
. 2025 Mar;
PMID: 40033850
SprA1 and SprA2 are small hydrophobic peptides that belong to the type I toxin-antitoxin systems expressed by Staphylococcus aureus. Both peptides induce S. aureus death when overexpressed. Although they share...
2.
Mascary J, Bordeau V, Nicolas I, Verdier M, Rocheteau P, Cattoir V
JAC Antimicrob Resist
. 2024 Feb;
6(1):dlae025.
PMID: 38410249
Objectives: Assessing the therapeutic potential of a novel antimicrobial pseudopeptide, Pep16, both and for the treatment of septic arthritis caused by . Methods: Seven clinical isolates of (two MRSA and...
3.
Chosidow S, Fantin B, Nicolas I, Mascary J, Chau F, Bordeau V, et al.
Antibiotics (Basel)
. 2023 Jan;
12(1).
PMID: 36671282
Colistin is a drug of last resort to treat extreme drug-resistant Enterobacterales, but is limited by dose-dependent toxicity and the emergence of resistance. A recently developed antimicrobial pseudopeptide, Pep16, which...
4.
Nicolas I, Bordeau V, Bondon A, Baudy-Floch M, Felden B
PLoS Biol
. 2019 Jul;
17(7):e3000337.
PMID: 31287812
Antibiotics are a medical wonder, but an increasing frequency of resistance among most human pathogens is rendering them ineffective. If this trend continues, the consequences for public health and for...
5.
Germain-Amiot N, Augagneur Y, Camberlein E, Nicolas I, Lecureur V, Rouillon A, et al.
Nucleic Acids Res
. 2018 Dec;
47(4):1759-1773.
PMID: 30544243
Bacterial type I toxin-antitoxin (TA) systems are widespread, and consist of a stable toxic peptide whose expression is monitored by a labile RNA antitoxin. We characterized Staphylococcus aureus SprA2/SprA2AS module,...
6.
Aubert E, Espinosa E, Nicolas I, Jeannin O, Fourmigue M
Faraday Discuss
. 2017 Jul;
203:389-406.
PMID: 28745381
We compare here the halogen bond characteristics of bimolecular adducts involving either N-bromo- or N-iodosaccharin as strong halogen bond donors, with 4-picoline as a common XB acceptor. In the NBSac·Pic...
7.
Ruan M, Nicolas I, Baudy-Floch M
Springerplus
. 2016 Feb;
5:55.
PMID: 26835235
Dendritic oligopeptides have been reported as useful building blocks for many interactions. Starting from hydrazine, we described an approach to create new dendritic pseudopeptides linked with biological systems, such as...