Irene C Schneider
Overview
Explore the profile of Irene C Schneider including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
331
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Recent Articles
1.
Wang N, Patel H, Schneider I, Kai X, Varshney A, Zhou L
Antib Ther
. 2021 Jun;
4(2):90-100.
PMID: 34169228
Background: CD3-based bispecific T cell engagers (bsTCEs) are one of the most promising bispecific antibodies for effective cancer treatments. To elicit target-specific T cell-mediated cytotoxicity, these bsTCEs contain at least...
2.
Hartmann J, Munch R, Freiling R, Schneider I, Dreier B, Samukang W, et al.
Mol Ther Methods Clin Dev
. 2021 Jun;
21:728.
PMID: 34141827
[This corrects the article DOI: 10.1016/j.omtm.2018.07.001.].
3.
Frank A, Braun A, Scheib L, Agarwal S, Schneider I, Fusil F, et al.
Blood Adv
. 2020 Nov;
4(22):5702-5715.
PMID: 33216892
Genetic modification of T lymphocytes is a key issue in research and therapy. Conventional lentiviral vectors (LVs) are neither selective for T cells nor do they modify resting or minimally...
4.
Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider I, Schmitz H, et al.
Med Microbiol Immunol
. 2020 Sep;
209(6):681-691.
PMID: 32918599
Chimeric Antigen Receptor (CAR)-redirected T cells show great efficacy in the patient-specific therapy of hematologic malignancies. Here, we demonstrate that a DARPin with specificity for CD4 specifically redirects and triggers...
5.
Hartmann J, Munch R, Freiling R, Schneider I, Dreier B, Samukange W, et al.
Mol Ther Methods Clin Dev
. 2018 Aug;
10:128-143.
PMID: 30101151
Delivering genes selectively to the therapeutically relevant cell type is among the prime goals of vector development. Here, we present a high-throughput selection and screening process that identifies designed ankyrin...
6.
Hanauer J, Rengstl B, Kleinlutzum D, Reul J, Pfeiffer A, Friedel T, et al.
Oncotarget
. 2018 Mar;
9(16):12971-12981.
PMID: 29560124
Classical Hodgkin lymphoma (cHL) is a hematopoietic malignancy with a characteristic cellular composition. The tumor mass is made up of infiltrated lymphocytes and other cells of hematologic origin but only...
7.
Schneider I, Hartmann J, Braun G, Stitz J, Klamp T, Bihi M, et al.
Biotechnol J
. 2017 Nov;
13(3):e1700345.
PMID: 29131519
Virus-like particles (VLPs) displaying foreign antigens have become an important tool in vaccination including the induction of immune responses against self-antigens. Claudin 6 (CLDN6) has been identified as tumor-associated antigen...
8.
Muik A, Reul J, Friedel T, Muth A, Hartmann K, Schneider I, et al.
Biomaterials
. 2017 Aug;
144:84-94.
PMID: 28825979
We have established a novel approach for the covalent coupling of large polypeptides to the surface of fully assembled adeno-associated viral gene transfer vector (AAV) particles via split-intein mediated protein-trans-splicing...
9.
Bender R, Muth A, Schneider I, Friedel T, Hartmann J, Pluckthun A, et al.
PLoS Pathog
. 2016 Jun;
12(6):e1005641.
PMID: 27281338
Receptor-targeted lentiviral vectors (LVs) can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties...
10.
Friedel T, Jung-Klawitter S, Sebe A, Schenk F, Modlich U, Ivics Z, et al.
Stem Cells Dev
. 2016 Mar;
25(9):729-39.
PMID: 26956718
Cultures of induced pluripotent stem cells (iPSCs) often contain cells of varying grades of pluripotency. We present novel lentiviral vectors targeted to the surface receptor CD30 (CD30-LV) to transfer genes...