Irena Ivanovska
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Explore the profile of Irena Ivanovska including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
925
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Recent Articles
1.
Wang M, Ivanovska I, Vashisth M, Discher D
APL Bioeng
. 2022 Jun;
6(2):021504.
PMID: 35719698
Two meters of DNA in each of our cells must be protected against many types of damage. Mechanoprotection is increasingly understood to be conferred by the nuclear lamina of intermediate...
2.
Huang M, Smith A, Watson M, Bhandari R, Baugh L, Ivanovska I, et al.
Arthritis Rheumatol
. 2022 Feb;
74(7):1245-1256.
PMID: 35212485
Objective: The development of precision therapeutics for systemic sclerosis (SSc) has been hindered by the lack of models that accurately mimic the disease in vitro. This study was undertaken to...
3.
Nair P, Alvey C, Jin X, Irianto J, Ivanovska I, Discher D
Bioconjug Chem
. 2018 Feb;
29(4):914-927.
PMID: 29451777
Drug resistance and relapse is common in cancer treatments with chemotherapeutics, and while drug combinations with naturally occurring, differentiation-inducing retinoic acid (RA) provide remission-free cures for one type of liquid...
4.
Elwood F, Witter D, Piesvaux J, Kraybill B, Bays N, Alpert C, et al.
J Pharmacol Exp Ther
. 2017 Feb;
361(2):229-244.
PMID: 28193636
Reversible janus associated kinase (JAK) inhibitors such as tofacitinib and decernotinib block cytokine signaling and are efficacious in treating autoimmune diseases. However, therapeutic doses are limited due to inhibition of...
5.
Shin J, Swift J, Ivanovska I, Spinler K, Buxboim A, Discher D
Differentiation
. 2013 Jun;
86(3):77-86.
PMID: 23790394
Adult stem cells and progenitors are of great interest for their clinical application as well as their potential to reveal deep sensitivities to microenvironmental factors. The bone marrow is a...
6.
Ivanovska I, Zhang C, Liu A, Wong K, Lee N, Lewis P, et al.
PLoS One
. 2011 Sep;
6(9):e24582.
PMID: 21949730
Biomarkers derived from gene expression profiling data may have a high false-positive rate and must be rigorously validated using independent clinical data sets, which are not always available. Although animal...
7.
Lamb J, Zhang C, Xie T, Wang K, Zhang B, Hao K, et al.
PLoS One
. 2011 Jul;
6(7):e20090.
PMID: 21750698
Background: In hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes...
8.
Luk J, Burchard J, Zhang C, Liu A, Wong K, Shek F, et al.
J Biol Chem
. 2011 Jul;
286(35):30706-30713.
PMID: 21737452
Hepatocellular carcinoma (HCC) is a heterogeneous and highly aggressive malignancy, for which there are no effective cures. Identification of a malignant stemlike subtype of HCC may offer patients with a...
9.
Ivanovska I, Swift J, Harada T, Pajerowski J, Discher D
Methods Cell Biol
. 2010 Sep;
98:207-20.
PMID: 20816236
The genome is virtually identical in all cells within an organism, with epigenetic changes contributing largely to the plasticity in gene expression during both development and aging. These changes include...
10.
Stadler B, Ivanovska I, Mehta K, Song S, Nelson A, Tan Y, et al.
Stem Cells Dev
. 2010 Feb;
19(7):935-50.
PMID: 20128659
Studies of embryonic stem cells (ESCs) reveal that these cell lines can be derived from differing stages of embryonic development. We analyzed common changes in the expression of microRNAs (miRNAs)...