Iqra Sarfraz
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Explore the profile of Iqra Sarfraz including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
700
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Recent Articles
1.
Sarfraz I, Rasul A, Jabeen F, Sultana T, Adem S
Molecules
. 2022 Oct;
27(20).
PMID: 36296707
The reliance of tumor cells on aerobic glycolysis is one of the emerging hallmarks of cancer. Pyruvate kinase M2 (PKM2), an important enzyme of glycolytic pathway, is highly expressed in...
2.
Adem S, Eyupoglu V, Ibrahim I, Sarfraz I, Rasul A, Ali M, et al.
Comput Biol Med
. 2022 Apr;
145:105452.
PMID: 35364308
SARS-CoV-2, a rapidly spreading new strain of human coronavirus, has affected almost all the countries around the world. The lack of specific drugs against SARS-CoV-2 is a significant hurdle towards...
3.
Sarfraz I, Rasul A, Hussain G, Shah M, Nageen B, Jabeen F, et al.
Comb Chem High Throughput Screen
. 2021 Aug;
25(7):1181-1186.
PMID: 34391377
Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis...
4.
Rasul A, Riaz A, Wei W, Sarfraz I, Hassan M, Li J, et al.
Biomed Res Int
. 2021 Jun;
2021:5514669.
PMID: 34136566
Pyruvate kinase (PK), a key enzyme that determines glycolytic activity, has been known to support the metabolic phenotype of tumor cells, and specific pyruvate kinase isoform M2 (PKM2) has been...
5.
Adnan M, Rasul A, Shah M, Hussain G, Asrar M, Riaz A, et al.
Anticancer Agents Med Chem
. 2021 Apr;
22(1):30-39.
PMID: 33874875
The identification and development of radioprotective agents have emerged as a subject matter of research during recent years due to the growing usage of ionizing radiation in different areas of...
6.
Batool R, Rasul A, Hussain G, Shah M, Nageen B, Sarfraz I, et al.
Curr Pharm Des
. 2021 Feb;
27(22):2628-2634.
PMID: 33573548
Natural products have served as a limitless reservoir of bioactive scaffolds for drug discovery against several disorders. Furanodiene is a bioactive natural product isolated from several plants of genus Curcuma....
7.
Adnan M, Rasul A, Hussain G, Shah M, Sarfraz I, Nageen B, et al.
Curr Drug Targets
. 2020 Oct;
22(5):488-504.
PMID: 33050858
Nature has provided prodigious reservoirs of pharmacologically active compounds for drug development since times. Physcion and physcion 8-O-β-D-glucopyranoside (PG) are bioactive natural anthraquinones which exert anti-inflammatory and anticancer properties with...
8.
Adem S, Eyupoglu V, Sarfraz I, Rasul A, Zahoor A, Ali M, et al.
Phytomedicine
. 2020 Sep;
85:153310.
PMID: 32948420
Background: SARS-CoV-2, an emerging strain of coronavirus, has affected millions of people from all the continents of world and received worldwide attention. This emerging health crisis calls for the urgent...
9.
Adnan M, Rasul A, Hussain G, Shah M, Zahoor M, Anwar H, et al.
Food Chem Toxicol
. 2020 Aug;
145:111642.
PMID: 32783998
Natural products, being richly endowed with curative powers, have become spotlight for biomedical and pharmaceutical research to develop novel therapeutics during recent years. Ginkgetin (GK), a natural non-toxic biflavone, has...
10.
Sarfraz A, Rasul A, Sarfraz I, Shah M, Hussain G, Shafiq N, et al.
Environ Res
. 2020 Aug;
190:110017.
PMID: 32768475
Nature as an infinite treasure of chemotypes and pharmacophores will continue to play an imperative role in the drug discovery. Natural products (NPs) such as plant and fungal metabolites have...