Ioannis M Koukourakis
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Explore the profile of Ioannis M Koukourakis including associated specialties, affiliations and a list of published articles.
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33
Citations
125
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Recent Articles
1.
Zygogianni A, Koukourakis I, Liakouli Z, Desse D, Georgakopoulos I, Armpilia C, et al.
Biomedicines
. 2025 Feb;
13(2).
PMID: 40002930
: The lung is the most common site of metastases, regardless of the cancer subtype. Treating oligometastatic disease with surgery or stereotactic ablative radiotherapy (SABR) may improve patient survival. :...
2.
Koukourakis I, Georgakopoulos I, Desse D, Tiniakos D, Kouloulias V, Zygogianni A
Radiat Oncol J
. 2025 Jan;
42(4):263-272.
PMID: 39748527
Purpose: Neoadjuvant radiotherapy (RT) or chemoradiotherapy (CRT) is the standard treatment for locally advanced rectal adenocarcinoma. The recent emerging data on preoperative immunotherapy as an effective therapeutic modality for mismatch...
3.
Nanos C, Koukourakis I, Mulita A, Avgousti R, Kouloulias V, Zygogianni A, et al.
Curr Oncol
. 2024 Oct;
31(10):5774-5788.
PMID: 39451733
Radiotherapy (RT)-induced lymphopenia may hinder the anti-tumor immune response. Preoperative RT or chemo-RT (CRT) for locally advanced rectal cancer is a standard therapeutic approach, while immunotherapy has been approved for...
4.
Zygogianni A, Koukourakis I, Georgakopoulos J, Armpilia C, Liakouli Z, Desse D, et al.
Cancers (Basel)
. 2024 Sep;
16(18).
PMID: 39335198
Background/objectives: Surgery is the primary treatment for early-stage lung cancer. Patients with medically inoperable lung carcinomas and patients who refuse to undergo surgery are treated with definite radiotherapy. Stereotactic ablative...
5.
Koukourakis I, Xanthopoulou E, Koukourakis M, Tiniakos D, Kouloulias V, Zygogianni A
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672465
The IFN-type-I pathway is involved in radiotherapy (RT)-mediated immune responses. Large RT fractions have been suggested to potently induce this pathway. Neoadjuvant hypofractionated short-course (scRT) and conventional long-course (lcRT) RT...
6.
Koukourakis I, Gkegka A, Giatromanolaki A, Koukourakis M
Int J Radiat Biol
. 2024 Feb;
100(5):736-743.
PMID: 38394349
Introduction: The role of the immune system in the efficacy of radiotherapy (RT) has been well established. We examined the role of neoplasia-related and treatment-induced lymphopenia in the outcome of...
7.
Filippatos K, Koukourakis I, Anevlavis S, Giaktzidis A, Koukourakis M
Cancers (Basel)
. 2023 Oct;
15(20).
PMID: 37894449
Large fractions of radiotherapy of 8 Gy (ultra-hypofractionated RT, ultra-hypoRT) promote anti-tumor immune responses that have been clinically substantiated in combination trials with immune checkpoint inhibitors (ICIs). In the current...
8.
Koukourakis M, Xanthopoulou E, Koukourakis I, Fortis S, Kesesidis N, Kakouratos C, et al.
Curr Oncol
. 2023 Oct;
30(10):8902-8915.
PMID: 37887543
Using next-generation sequencing (NGS), we investigated DNA mutations in the plasma tumor cell-free circulating DNA (ctDNA) of 38 patients with inoperable squamous cell head neck cancer (SCHNC) before and after...
9.
Koukourakis I, Xanthopoulou E, Sgouras T, Kouroupi M, Giatromanolaki A, Kouloulias V, et al.
Br J Cancer
. 2023 Oct;
129(11):1852-1862.
PMID: 37838813
Background: Rectal cancer treated with preoperative radiotherapy (RT) provides an interesting model to study changes induced on cancer cell immuno-phenotype that could be exploited by immunotherapy interventions to improve prognosis....
10.
Koukourakis I, Platoni K, Kouloulias V, Arelaki S, Zygogianni A
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834336
Stem cells differentiate into mature organ/tissue-specific cells at a steady pace under normal conditions, but their growth can be accelerated during the process of tissue healing or in the context...