Ioanna Tzoulaki
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Explore the profile of Ioanna Tzoulaki including associated specialties, affiliations and a list of published articles.
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228
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15007
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Recent Articles
1.
Wu S, Smith A, Huang J, Otto G, Ko Y, Yarmolinsky J, et al.
medRxiv
. 2025 Jan;
PMID: 39763524
South Asians are at higher risk of dyslipidaemia-a modifiable risk factor for cardiovascular diseases (CVDs). We aimed to identify protein targets for dyslipidaemia and CVDs in this population. We used...
2.
Manou M, Papagiannopoulos C, Chalitsios C, Asimakopoulos A, Markozannes G, Bullo M, et al.
J Am Heart Assoc
. 2024 Nov;
13(23):e036573.
PMID: 39575750
Background: The underlying biological mechanisms linking blood pressure (BP) and cardiovascular diseases (CVD) are only partly understood. We aimed to identify metabolic signatures associated with systolic and diastolic BP and...
3.
Antonatos C, Koskeridis F, Ralliou C, Evangelou E, Grafanaki K, Georgiou S, et al.
Front Genet
. 2024 Nov;
15:1451679.
PMID: 39568675
Introduction: Polygenic Risk Scores (PRS) are an emerging tool for predicting an individual's genetic risk to a complex trait. Several methods have been proposed to construct and calculate these scores....
4.
Koskeridis F, Fancy N, Tan P, Meena D, Evangelou E, Elliott P, et al.
Nat Commun
. 2024 Nov;
15(1):9827.
PMID: 39537608
Several cardiovascular traits and diseases co-occur with Alzheimer's disease. We mapped their shared genetic architecture using multi-trait genome-wide association studies. Subsequent fine-mapping and colocalisation highlighted 16 genetic loci associated with...
5.
Yan R, Liu L, Tzoulaki I, Fan J, Targher G, Yuan Z, et al.
Liver Int
. 2024 Nov;
45(4):e16150.
PMID: 39487684
Background And Aims: Glucagon-like peptide-1 receptor (GLP1R) agonists and glucose-dependent insulinotropic polypeptide receptor (GIPR) agonists may help treat metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH). However,...
6.
Sau A, Pastika L, Sieliwonczyk E, Patlatzoglou K, Ribeiro A, McGurk K, et al.
Lancet Digit Health
. 2024 Oct;
6(11):e791-e802.
PMID: 39455192
Background: Artificial intelligence (AI)-enabled electrocardiography (ECG) can be used to predict risk of future disease and mortality but has not yet been adopted into clinical practice. Existing model predictions do...
7.
Gunasekaran T, Meena D, Lee A, Wu S, Dumitrescu L, Sperling R, et al.
medRxiv
. 2024 Oct;
PMID: 39417126
Background: Genetic research on Alzheimer's disease (AD) has primarily focused on amyloid-β (Aβ) pathogenesis, with fewer studies exploring tau pathology. Elucidating the genetic basis of tau pathology could identify novel...
8.
Rontogianni M, Gill D, Bouras E, Asimakopoulos A, Tzoulaki I, Karhunen V, et al.
iScience
. 2024 Sep;
27(10):110704.
PMID: 39319267
We investigated the effects of 35 inflammatory cytokines on respiratory outcomes, including COVID-19, asthma (atopic and non-atopic), chronic obstructive pulmonary disease (COPD), and pulmonary function indices, using Mendelian randomization and...
9.
Wu S, Meena D, Yarmolinsky J, Gill D, Smith A, Dib M, et al.
J Am Heart Assoc
. 2024 Aug;
13(16):e035008.
PMID: 39119976
Background: Circulating plasma proteins are clinically useful biomarkers for stroke risk. We examined the causal links between plasma proteins and stroke risk in individuals of South Asian ancestry. Methods And...
10.
Meena D, Huang J, Dib M, Chirinos J, Jia M, Chauhan G, et al.
J Am Heart Assoc
. 2024 Jul;
13(14):e032192.
PMID: 38979809
Background: Early age at menarche (AAM) has been associated with a higher risk of carotid artery intima-media thickness (cIMT), an indicator of subclinical vascular disease, albeit the mechanisms underlying this...