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Inigo Ayestaran

Explore the profile of Inigo Ayestaran including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 74
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Recent Articles
1.
Lloyd R, Urban V, Munoz-Martinez F, Ayestaran I, Thomas J, de Renty C, et al.
Nucleic Acids Res . 2021 Jul; 49(15):8665-8683. PMID: 34329458
The protein kinase ATR plays pivotal roles in DNA repair, cell cycle checkpoint engagement and DNA replication. Consequently, ATR inhibitors (ATRi) are in clinical development for the treatment of cancers,...
2.
Ayestaran I, Galhoz A, Spiegel E, Sidders B, Dry J, Dondelinger F, et al.
Patterns (N Y) . 2020 Nov; 1(5):100065. PMID: 33205120
High-throughput drug screens in cancer cell lines test compounds at low concentrations, thereby enabling the identification of drug-sensitivity biomarkers, while resistance biomarkers remain underexplored. Dissecting meaningful drug responses at high...
3.
Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, et al.
Nature . 2019 Sep; 573(7774):416-420. PMID: 31511699
Despite major progress in defining the functional roles of genes, a complete understanding of their influences is far from being realized, even in relatively simple organisms. A major milestone in...