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Ingolf Reim

Explore the profile of Ingolf Reim including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 487
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Recent Articles
1.
Frasch M, Ismat A, Reim I, Raufer J
Development . 2023 Aug; 150(18). PMID: 37642089
Development of the visceral musculature of the Drosophila midgut encompasses a closely coordinated sequence of migration events of cells from the trunk and caudal visceral mesoderm that underlies the formation...
2.
Rose M, Domsch K, Bartle-Schultheis J, Reim I, Schaub C
Cell Rep . 2022 Jan; 38(4):110295. PMID: 35081347
Genesis of syncytial muscles is typically considered as a paradigm for an irreversible developmental process. Notably, transdifferentiation of syncytial muscles is naturally occurring during Drosophila development. The ventral longitudinal heart-associated...
3.
Espinola S, Gotz M, Bellec M, Messina O, Fiche J, Houbron C, et al.
Nat Genet . 2021 Apr; 53(4):477-486. PMID: 33795867
Acquisition of cell fate is thought to rely on the specific interaction of remote cis-regulatory modules (CRMs), for example, enhancers and target promoters. However, the precise interplay between chromatin structure...
4.
Jammrath J, Reim I, Saumweber H
PLoS One . 2020 May; 15(5):e0233719. PMID: 32469960
The formation of a tube-like structure is a basic step in the making of functional hearts in vertebrates and invertebrates and therefore, its understanding provides important information on heart development...
5.
Schwarz B, Hollfelder D, Scharf K, Hartmann L, Reim I
Elife . 2018 Jun; 7. PMID: 29869981
For coordinated circulation, vertebrate and invertebrate hearts require stereotyped arrangements of diverse cell populations. This study explores the process of cardiac cell diversification in the heart, focusing on the two...
6.
Domsch K, Acs A, Obermeier C, Nguyen H, Reim I
PLoS One . 2017 Mar; 12(3):e0173733. PMID: 28282454
The proper differentiation and maintenance of myofibers is fundamental to a functional musculature. Disruption of numerous mostly structural factors leads to perturbations of these processes. Among the limited number of...
7.
Kahn T, Dorafshan E, Schultheis D, Zare A, Stenberg P, Reim I, et al.
Nucleic Acids Res . 2016 Aug; 44(21):10132-10149. PMID: 27557709
Polycomb Group (PcG) proteins are epigenetic repressors essential for control of development and cell differentiation. They form multiple complexes of which PRC1 and PRC2 are evolutionary conserved and obligatory for...
8.
Schaub C, Marz J, Reim I, Frasch M
Curr Biol . 2015 Feb; 25(4):488-94. PMID: 25660543
Only few examples of transdifferentiation, which denotes the conversion of one differentiated cell type to another, are known to occur during normal development, and more often, it is associated with...
9.
Boukhatmi H, Schaub C, Bataille L, Reim I, Frendo J, Frasch M, et al.
Development . 2014 Sep; 141(19):3761-71. PMID: 25209244
The T-box transcription factor Tbx1 and the LIM-homeodomain transcription factor Islet1 are key components in regulatory circuits that generate myogenic and cardiogenic lineage diversity in chordates. We show here that...
10.
Hollfelder D, Frasch M, Reim I
BMC Dev Biol . 2014 Jun; 14:26. PMID: 24935095
Background: The Drosophila heart (dorsal vessel) is a relatively simple tubular organ that serves as a model for several aspects of cardiogenesis. Cardiac morphogenesis, proper heart function and stability require...