Ines M Aparicio
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Explore the profile of Ines M Aparicio including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
66
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Recent Articles
1.
Pena F, Martin-Cano F, Becerro-Rey L, da Silva-Alvarez E, Gaitskell-Phillips G, Aparicio I, et al.
Antioxidants (Basel)
. 2025 Feb;
14(2).
PMID: 40002411
Stallion spermatozoa are cells which exhibit intense metabolic activity, where oxidative phosphorylation in the mitochondria is the primary ATP generator. However, metabolism must be viewed as a highly interconnected network...
2.
Pena F, Martin-Cano F, Becerro-Rey L, da Silva-Alvarez E, Gaitskell-Phillips G, Ortega-Ferrusola C, et al.
J Equine Vet Sci
. 2024 Oct;
143:105204.
PMID: 39384120
Although stallion spermatozoa are now recognized as highly dependent on oxidative phosphorylation for ATP production in the mitochondria, most extenders in use contain supraphysiological concentrations of glucose as the main...
3.
Becerro-Rey L, Martin-Cano F, Sancler-Silva Y, Gil M, Ortega-Ferrusola C, Aparicio I, et al.
Theriogenology
. 2024 Aug;
229:127-137.
PMID: 39178614
Background: Conservation of equine semen in the liquid state is a central procedure in horse breeding and constitutes the basis of associated reproductive technologies. The intense mitochondrial activity of the...
4.
Aparicio I, Rojo-Dominguez P, Castillejo-Rufo A, Pena F, Tapia J
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674454
Despite its importance in somatic cells and during spermatogenesis, little is known about the role that autophagy may play in ejaculated spermatozoa. Our aim was to investigate whether the molecular...
5.
Ortiz-Rodriguez J, Martin-Cano F, Ortega-Ferrusola C, Masot J, Redondo E, Gazquez A, et al.
Biol Reprod
. 2019 Apr;
101(1):208-222.
PMID: 30998234
Oxidative stress is considered a major mechanism causing sperm damage during cryopreservation and storage, and underlies male factor infertility. Currently, oxidative stress is no longer believed to be caused only...
6.
Gallardo Bolanos J, Balao da Silva C, Martin Munoz P, Morillo Rodriguez A, Plaza Davila M, Rodriguez-Martinez H, et al.
Reproduction
. 2014 May;
148(2):221-35.
PMID: 24850868
AKT, also referred to as protein kinase B (PKB or RAC), plays a critical role in controlling cell survival and apoptosis. To gain insights into the mechanisms regulating sperm survival...
7.
Miro-Moran A, Jardin I, Ortega-Ferrusola C, Salido G, Pena F, Tapia J, et al.
PLoS One
. 2012 Jun;
7(5):e37713.
PMID: 22662198
The role of cAMP in spermatic functions was classically thought to be mediated exclusively through the activation of Protein Kinase A (PKA). However, it has recently been shown that cAMP...
8.
Gallardo Bolanos J, Miro Moran A, Balao da Silva C, Morillo Rodriguez A, Plaza Davila M, Aparicio I, et al.
PLoS One
. 2012 Feb;
7(1):e30688.
PMID: 22292020
Apoptosis has been recognized as a cause of sperm death during cryopreservation and a cause of infertility in humans, however there is no data on its role in sperm death...
9.
Bragado M, Aparicio I, Gil M, Garcia-Marin L
J Cell Biochem
. 2009 Nov;
109(1):65-73.
PMID: 19911376
The cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and phosphatidylinositol 3-kinase (PI3K) pathways control most relevant functions in male germ cells including motility. Recently we demonstrated that phosphorylation state...