Ines Batinic-Haberle
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Explore the profile of Ines Batinic-Haberle including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Soares R, Pinto J, Amaro F, Manguinhas R, Gil N, Rosell R, et al.
Biochem Pharmacol
. 2024 Jul;
227:116424.
PMID: 39004232
Redox-based cancer therapeutic strategies aim to raise reactive oxygen species (ROS) levels in cancer cells, thus modifying their redox status, and eventually inducing cell death. Promising compounds, known as superoxide...
2.
Noh S, Lim J, Shin S, Kim Y, Park W, Batinic-Haberle I, et al.
Antioxidants (Basel)
. 2024 Apr;
13(4).
PMID: 38671924
Manganese porphyrins reportedly exhibit synergic effects when combined with irradiation. However, an in-depth understanding of intratumoral heterogeneity and immune pathways, as affected by Mn porphyrins, remains limited. Here, we explored...
3.
Shen X, Wang J, Deng B, Chen S, John C, Zhao Z, et al.
Gynecol Oncol
. 2024 Mar;
183:93-102.
PMID: 38555710
Objective: Uterine serous carcinoma is a highly aggressive non-endometrioid subtype of endometrial cancer with poor survival rates overall, creating a strong need for new therapeutic strategies to improve outcomes. High-dose...
4.
Abbas G, Alibrahim F, Kankouni R, Al-Belushi S, Al-Mutairi D, Tovmasyan A, et al.
Free Radic Res
. 2023 Nov;
57(6-12):487-499.
PMID: 38035627
Coordination of metal ions by the tetrapyrrolic macrocyclic ring of porphyrin-based photosensitizers (PSs) affects their photophysical properties and consequently, their photodynamic activity. Diamagnetic metals increase the singlet oxygen quantum yield...
5.
Li X, Duan W, Du L, Chu D, Wang P, Yang Z, et al.
Antioxidants (Basel)
. 2023 Oct;
12(10).
PMID: 37891940
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor...
6.
Soares R, Manguinhas R, Costa J, Saraiva N, Gil N, Rosell R, et al.
Cancers (Basel)
. 2023 Aug;
15(15).
PMID: 37568630
Manganese(III) porphyrin MnTnBuOE-2-PyP (MnBuOE, BMX-001) is a third-generation redox-active cationic substituted pyridylporphyrin-based drug with a good safety/toxicity profile that has been studied in several types of cancer. It is currently...
7.
Sharma S, Sharma P, Subedi U, Bhattarai S, Miller C, Manikandan S, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047131
Myocardial ischemia-reperfusion injury (I/R) causes damage to cardiomyocytes through oxidative stress and apoptosis. We investigated the cardioprotective effects of MnTnBuOE-2-PyP (BMX-001), a superoxide dismutase mimic, in an in vitro model...
8.
Soares R, Manguinhas R, Costa J, Saraiva N, Gil N, Rosell R, et al.
Antioxidants (Basel)
. 2022 Nov;
11(11).
PMID: 36358570
The manganese(III) porphyrin MnTnHex-2-PyP (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including...
9.
Wang P, Li Y, Yan B, Yang Z, Li L, Cao Z, et al.
Biology (Basel)
. 2022 Sep;
11(7).
PMID: 36101338
Introduction Cardiac arrest (CA) and resuscitation induces global cerebral ischemia and reperfusion, causing neurologic deficits or death. Manganese porphyrins, superoxide dismutase mimics, are reportedly able to effectively reduce ischemic injury...
10.
Chaiswing L, Yarana C, Clair W, Tovmasyan A, Batinic-Haberle I, Spasojevic I, et al.
Oxid Med Cell Longev
. 2022 Jul;
2022():9664636.
PMID: 35898616
We have employed a redox-active MnP (MnTnBuOE-2-PyP, Mn(III) meso-tetrakis (N-n-butoxyethylpyridinium-2-yl) porphyrin) frequently identified as superoxide dismutase mimic or BMX-001, to explore the redox status of normal ovarian cell in relation...