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Ineke Seghers

Explore the profile of Ineke Seghers including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 26
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Recent Articles
1.
Ford P, Kreuter M, Brown K, Wuyts W, Wijsenbeek M, Israel-Biet D, et al.
ERJ Open Res . 2024 Jan; 10(1). PMID: 38288082
Background: There is no standard definition of respiratory-related hospitalisation, a common end-point in idiopathic pulmonary fibrosis (IPF) clinical trials. As diverse aetiologies and complicating comorbidities can present similarly, external adjudication...
2.
Maher T, Ford P, Brown K, Costabel U, Cottin V, Danoff S, et al.
JAMA . 2023 May; 329(18):1567-1578. PMID: 37159034
Importance: There is a major need for effective, well-tolerated treatments for idiopathic pulmonary fibrosis (IPF). Objective: To assess the efficacy and safety of the autotaxin inhibitor ziritaxestat in patients with...
3.
Helmer E, Karimian N, Van Assche K, Seghers I, Le Tallec S, Cherala G, et al.
Clin Pharmacol Ther . 2022 Jun; 112(4):901-908. PMID: 35713964
In vitro signals indicate that ziritaxestat is a weak cytochrome P450 (CYP) 3A4 inhibitor and inducer. Therefore, potential drug-drug interactions (DDIs) with oral contraceptives were examined at a time when...