Indranil Malik
Overview
Explore the profile of Indranil Malik including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
346
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats
Tseng Y, Krans A, Malik I, Deng X, Yildirim E, Ovunc S, et al.
Nucleic Acids Res
. 2024 Feb;
52(10):5928-5949.
PMID: 38412259
A GGGGCC (G4C2) hexanucleotide repeat expansion in C9ORF72 causes amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD), while a CGG trinucleotide repeat expansion in FMR1 leads to the neurodegenerative disorder Fragile...
2.
Sharma G, Chodvadiya J, Malik I
J Bacteriol
. 2024 Jan;
206(2):e0040123.
PMID: 38294238
This commentary discusses a comprehensive history of the first-ever use of pertinent words directly related to DNA, such as desoxyribose, deoxyribose, desoxyribonucleic acid, and deoxyribonucleic acid. With almost 100 years...
3.
Qiu C, Arora P, Malik I, LaPeruta A, Pavlovic E, Ugochukwu S, et al.
Nucleic Acids Res
. 2024 Jan;
52(5):2546-2564.
PMID: 38214235
Thiolutin is a natural product transcription inhibitor with an unresolved mode of action. Thiolutin and the related dithiolopyrrolone holomycin chelate Zn2+ and previous studies have concluded that RNA Polymerase II...
4.
Malik I, Tseng Y, Wieland C, Green K, Zheng K, Calleja K, et al.
Neurobiol Dis
. 2023 Jun;
184:106212.
PMID: 37352983
Neurodegeneration in Fragile X-associated tremor/ataxia syndrome (FXTAS) is caused by a CGG trinucleotide repeat expansion in the 5' UTR of FMR1. Expanded CGG repeat RNAs form stable secondary structures, which...
5.
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats
Tseng Y, Malik I, Deng X, Krans A, Jansen-West K, Tank E, et al.
bioRxiv
. 2023 Jun;
PMID: 37333274
A GGGGCC (G4C2) hexanucleotide repeat expansion in causes amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD), while a CGG trinucleotide repeat expansion in leads to the neurodegenerative disorder Fragile X-associated tremor/ataxia...
6.
Kong H, Lim J, Linsalata A, Kang Y, Malik I, Allen E, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(22):e2118124119.
PMID: 35617426
Fragile X–associated tremor/ataxia syndrome (FXTAS) is a debilitating late-onset neurodegenerative disease in premutation carriers of the expanded CGG repeat in FMR1 that presents with a spectrum of neurological manifestations, such...
7.
Green K, Miller S, Malik I, Todd P
Hum Mol Genet
. 2022 Feb;
31(15):2521-2534.
PMID: 35220421
Repeat-associated non-AUG (RAN) translation of expanded repeat-mutation mRNA produces toxic peptides in neurons of patients suffering from neurodegenerative diseases. Recent findings indicate that RAN translation in diverse model systems is...
8.
Malik I, Tseng Y, Wright S, Zheng K, Ramaiyer P, Green K, et al.
EMBO Mol Med
. 2021 Sep;
13(11):e14163.
PMID: 34542927
Transcribed CGG repeat expansions cause neurodegeneration in Fragile X-associated tremor/ataxia syndrome (FXTAS). CGG repeat RNAs sequester RNA-binding proteins (RBPs) into nuclear foci and undergo repeat-associated non-AUG (RAN) translation into toxic...
9.
Malik I, Kelley C, Wang E, Todd P
Nat Rev Mol Cell Biol
. 2021 Jul;
22(9):644.
PMID: 34230651
No abstract available.
10.
Malik I, Kelley C, Wang E, Todd P
Nat Rev Mol Cell Biol
. 2021 Jun;
22(9):589-607.
PMID: 34140671
The human genome contains over one million short tandem repeats. Expansion of a subset of these repeat tracts underlies over fifty human disorders, including common genetic causes of amyotrophic lateral...