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Ilona Jaspers

Explore the profile of Ilona Jaspers including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 175
Citations 4343
Followers 0
Related Specialties
Pulmonary Medicine
Toxicology
Cell Biology
Top 10 Co-Authors
Meghan E Rebuli
Julia E Rager
Terry L Noah
M Ian Gilmour
Phillip W Clapp
Haibo Zhou
Neil E Alexis
Elise Hickman
Luisa E Brighton
Yong Ho Kim
Published In
Am J Physiol Lung Cell Mol Physiol
Chem Res Toxicol
Am J Respir Cell Mol Biol
PLoS One
Environ Health Perspect
Affiliations
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Recent Articles
1.
Exposure of Human Nasal Epithelial Cells to Polycyclic Aromatic Hydrocarbons Differentially Increases Markers of Inflammation and Expression of Aryl Hydrocarbon Pathway Genes
Rogers K, Ghosh A, Jaspers I
ACS Omega . 2025 Mar; 10(8):7734-7740. PMID: 40060875
Inhalation of polycyclic aromatic hydrocarbons (PAHs) derived from emissions of solid waste combustion is of public health concern, as PAHs are associated with respiratory cancers and inflammatory diseases. Here, we...
2.
TAME 2.0: expanding and improving online data science training for environmental health research
Payton A, Hickman E, Chappel J, Roell K, Koval L, Eaves L, et al.
Front Toxicol . 2025 Feb; 7:1535098. PMID: 40012886
Introduction: Data science training has the potential to propel environmental health research efforts into territories that remain untapped and holds immense promise to change our understanding of human health and...
3.
Respiratory extracellular vesicle isolation optimization through proteomic profiling of equine samples and identification of candidates for cell-of-origin studies
Hickman E, Carberry V, Carberry C, Cooper B, Mordant A, Mills A, et al.
PLoS One . 2025 Jan; 20(1):e0315743. PMID: 39854355
Growing evidence supports the importance of extracellular vesicle (EV) as mediators of communication in pathological processes, including those underlying respiratory disease. However, establishing methods for isolating and characterizing EVs remains...
4.
Profiling endogenous airway proteases and antiproteases and modeling proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples
Brocke S, Reidel B, Ehre C, Rebuli M, Robinette C, Schichlein K, et al.
PLoS One . 2024 Dec; 19(12):e0306197. PMID: 39739661
Imbalance of airway proteases and antiproteases has been implicated in diseases such as COPD and environmental exposures including cigarette smoke and ozone. To initiate infection, endogenous proteases are commandeered by...
5.
Evidence of sex differences in ozone-induced oxysterol and cytokine levels in differentiated human nasal epithelial cells
Dobson D, Perryman A, McNell E, Kim H, Porter N, Rebuli M, et al.
Am J Physiol Lung Cell Mol Physiol . 2024 Dec; 328(2):L207-L214. PMID: 39716873
Acute exposure to ozone (O) causes upper and lower airway inflammation. We and others have previously demonstrated that O oxidizes lipids, particularly cholesterol, into electrophilic oxysterols, such as secosterol B...
6.
E-cigarette, or Vaping, Product Use Associated Lung Injury: Epidemiology, Challenges, and Implications With COVID-19
Soerianto W, Jaspers I
Pediatr Pulmonol . 2024 Dec; 60(1):e27448. PMID: 39714069
Background: E-cigarette, or vaping products produce an aerosol by heating nicotine, or cannabis including tetrahydrocannabinol (THC) and cannabidiol (CBD), mixed with other chemicals that help make the aerosol. They are...
7.
Human Monocyte-Derived Macrophages Demonstrate Distinct Responses to Ambient Particulate Matter in a Polarization State- and Particle Seasonality-Specific Manner
Smyth T, Brocke S, Kim Y, Christianson C, Kovalcik K, Pancras J, et al.
Chem Res Toxicol . 2024 Dec; 38(1):73-90. PMID: 39704336
Macrophages are professional phagocytic immune cells that, following activation, polarize on a spectrum between the proinflammatory M1 and the proresolution M2 states. Macrophages have further been demonstrated to retain plasticity,...
8.
Simulated burn pit smoke condensates cause sustained impact on human airway epithelial cells
Ghosh A, Rogers Jr K, Gallant S, Brocke S, Speen A, Kim Y, et al.
Toxicol Sci . 2024 Dec; 204(1):2-8. PMID: 39673801
Inhalation of smoke from burn pits during military deployment is associated with several adverse pulmonary outcomes. We exposed human airway epithelial cells to smoke condensates from burn pit waste materials....
9.
Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome
Schichlein K, Kim H, Love C, Guhr Lee T, Esther Jr C, Porter N, et al.
Chem Res Toxicol . 2024 Nov; 37(12):1919-1923. PMID: 39528387
Melatonin vaping products, touted for their faster absorption than oral melatonin supplements, have been gaining popularity among adolescents as sleep aid. Here, we elucidated the response of human bronchial epithelial...
10.
Effect of prednisone on woodsmoke-induced sputum inflammation in healthy volunteers: A randomized, placebo-controlled pilot study
Noah T, Alexis N, Bennett W, Hernandez M, Burbank A, Li H, et al.
J Allergy Clin Immunol Glob . 2024 Nov; 4(1):100347. PMID: 39524042
Background: Inhalation of biomass smoke is associated with adverse respiratory effects in those with chronic pulmonary conditions. There are few published data regarding the effects of anti-inflammatory interventions on these...