Ilo E Leppik
Overview
Explore the profile of Ilo E Leppik including associated specialties, affiliations and a list of published articles.
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82
Citations
939
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Recent Articles
1.
ODwyer R, Leppik I, Eads P, Long Y, Birnbaum A
Epilepsy Behav
. 2024 Jul;
158:109913.
PMID: 38959744
Introduction: Residents in NH are more likely to be diagnosed with epilepsy or seizures, which are associated with higher mortality and complicate care. This setting provides unique challenges in the...
2.
Lyu X, Illamola S, Marino S, Leppik I, Dahmer S, Lehfeldt P, et al.
Curr Ther Res Clin Exp
. 2023 Aug;
99:100709.
PMID: 37538850
Background: Little is known about the distribution of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) to patients participating in state medical cannabis programs. The Minnesota cannabis program requires third-party testing of products...
3.
Leppik I, Birnbaum A, Svensden K, Eberly L
J Am Med Dir Assoc
. 2022 Jul;
23(9):1589.e11-1589.e15.
PMID: 35779573
Objective: The point prevalence of epilepsy is high in nursing homes (NH), but the incidence of epilepsy after admission is unknown. This study was done to determine the incidence of...
4.
Vuu I, Patterson E, Wu C, Zolkowska D, Leppik I, Rogawski M, et al.
J Pharmacol Exp Ther
. 2021 Dec;
380(2):104-113.
PMID: 34862270
Allopregnanolone (ALLO) is a neurosteroid that modulates synaptic and extrasynaptic GABA receptors. We hypothesize that ALLO may be useful as first-line treatment of status epilepticus (SE). Our objectives were to...
5.
Barkley C, Hu Z, Fieberg A, Eberly L, Birnbaum A, Leppik I, et al.
Epilepsy Behav
. 2020 Dec;
114(Pt A):107598.
PMID: 33268020
Introduction: Many commonly prescribed drugs cause cognitive deficits. We investigated whether parameters of the resting-state electroencephalogram (rsEEG) are related to the severity of cognitive impairments associated with administration of the...
6.
Callisto S, Illamola S, Birnbaum A, Barkley C, Bathena S, Leppik I, et al.
J Clin Pharmacol
. 2020 Apr;
60(9):1166-1176.
PMID: 32297992
Drug side effects that impair cognition can lead to diminished quality of life and discontinuation of therapy. Topiramate is an antiepileptic drug that elicits cognitive deficits more frequently than other...
7.
Birnbaum A, Karanam A, Marino S, Barkley C, Remmel R, Roslawski M, et al.
Epilepsia
. 2019 Jun;
60(8):1586-1592.
PMID: 31247132
Objective: To evaluate the pharmacokinetics of a purified oral cannabidiol (CBD) capsule administered with and without food in adults with refractory epilepsy. Methods: Adult patients who were prescribed CBD for...
8.
Roslawski M, Remmel R, Karanam A, Leppik I, Marino S, Birnbaum A
Ther Drug Monit
. 2018 Dec;
41(3):357-370.
PMID: 30520828
Background: A sensitive, robust method was developed and validated to quantitate 13 major natural cannabinoid parent and metabolite compounds in human plasma at or below 0.5 ng/mL. Methods: A liquid...
9.
Ahn J, Bathena S, Brundage R, Conway J, Leppik I, Birnbaum A
Epilepsy Res
. 2018 Oct;
147:115-118.
PMID: 30327119
Methods: CBZ concentration data collected from 60 nursing homes across the US were evaluated. Inclusion criteria included residency in a nursing home for at least 2 months, age 65 years...
10.
Leppik I
Epilepsia
. 2018 Aug;
59 Suppl 2:140-143.
PMID: 30159881
Children and the elderly (≥60 years of age) have the highest incidence of status epilepticus (SE). Because of their general health, elderly individuals are much more likely than younger (<60...