Ikjun Lee
Overview
Explore the profile of Ikjun Lee including associated specialties, affiliations and a list of published articles.
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18
Citations
87
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Recent Articles
1.
Choi S, Vu G, Nagar H, Kim S, Lee I, Piao S, et al.
Korean J Physiol Pharmacol
. 2024 Oct;
29(1):57-66.
PMID: 39482236
Schwann cells are the most abundant cells in the peripheral nervous system, maintaining the development, function and regeneration of peripheral nerves. Defects in these Schwann cells injury response potentially contribute...
2.
Jung B, You D, Lee I, Li D, Schill R, Ma K, et al.
Cell Rep
. 2023 Oct;
42(10):113196.
PMID: 37777963
Maintaining healthy adipose tissue is crucial for metabolic health, requiring a deeper understanding of adipocyte development and response to high-calorie diets. This study highlights the importance of TET3 during white...
3.
CRIF1 siRNA-Encapsulated PLGA Nanoparticles Suppress Tumor Growth in MCF-7 Human Breast Cancer Cells
Piao S, Lee I, Kim S, Park H, Nagar H, Choi S, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108616
Mitochondrial oxidative phosphorylation (OXPHOS) system dysfunction in cancer cells has been exploited as a target for anti-cancer therapeutic intervention. The downregulation of CR6-interacting factor 1 (CRIF1), an essential mito-ribosomal factor,...
4.
Lee I, Piao S, Kim S, Nagar H, Choi S, Kim M, et al.
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978833
Endothelial senescence impairs vascular function and thus is a primary event of age-related vasculature diseases. Isocitrate dehydrogenase 2 (IDH2) plays an important role in inducing alpha-ketoglutarate (α-KG) production and preserving...
5.
Kim S, Nagar H, Lee I, Choi S, Piao S, Jeon B, et al.
Evid Based Complement Alternat Med
. 2022 Oct;
2022:2885293.
PMID: 36199546
Breast cancer is the most common cancer and the leading cause of cancer-related mortality among females worldwide. Triple-negative breast cancer (TNBC) accounts for about 10-15% of all breast cancers and...
6.
Kim S, Lee I, Piao S, Nagar H, Choi S, Kim Y, et al.
Commun Biol
. 2022 Sep;
5(1):1002.
PMID: 36130994
Non-alcoholic fatty liver disease (NAFLD) is associated with hepatic metabolism dysfunction. However, the mechanistic role of miR204 in the development of NAFLD is unknown. We investigate the functional significance of...
7.
Choi S, Nagar H, Lee J, Kim S, Lee I, Piao S, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052866
Syndecan-2 (SDC2), a cell-surface heparin sulfate proteoglycan of the glycocalyx, is mainly expressed in endothelial cells. Although oxidative stress and inflammatory mediators have been shown to mediate dysfunction of the...
8.
Lee I, Piao S, Kim S, Nagar H, Choi S, Jeon B, et al.
Antioxidants (Basel)
. 2021 Nov;
10(11).
PMID: 34829516
Elevated plasma homocysteine levels can induce vascular endothelial dysfunction; however, the mechanisms regulating homocysteine metabolism in impaired endothelial cells are currently unclear. In this study, we deleted the essential mitoribosomal...
9.
Nagar H, Kim S, Lee I, Choi S, Piao S, Jeon B, et al.
PLoS One
. 2021 Aug;
16(8):e0256646.
PMID: 34437633
Rho GDP-dissociation inhibitor (RhoGDI), a downregulator of Rho family GTPases, prevents nucleotide exchange and membrane association. It is responsible for the activation of Rho GTPases, which regulate a variety of...
10.
Nagar H, Kim S, Lee I, Kim S, Choi S, Piao S, et al.
Sci Rep
. 2021 Jan;
11(1):500.
PMID: 33436666
Keloids are a type of aberrant skin scarring characterized by excessive accumulation of collagen and extracellular matrix (ECM), arising from uncontrolled wound healing responses. While typically non-pathogenic, keloids are occasionally...