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Iker Badiola

Explore the profile of Iker Badiola including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 234
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Recent Articles
1.
Demoures B, Soulet F, Descarpentrie J, Galeano-Otero I, Sanchez Collado J, Casado M, et al.
EMBO Mol Med . 2025 Feb; 17(3):504-534. PMID: 39962271
The adipokine apelin has been directly implicated in various physiological processes during embryogenesis and human cancers. Nevertheless, the importance of the conversion of its precursor proapelin to mature apelin in...
2.
Gonzalez A, Badiola I, Fullaondo A, Rodriguez J, Odriozola A
Adv Genet . 2024 Oct; 112:411-485. PMID: 39396842
Colorectal cancer (CRC) ranks second in incidence and third in cancer mortality worldwide. This situation, together with the understanding of the heterogeneity of the disease, has highlighted the need to...
3.
Badiola I
Adv Genet . 2024 Oct; 112:1-29. PMID: 39396835
Cancer is a complex disease that includes tumour and healthy cells surrounding and infiltrating the tumour. During cancer development, tumour cells release many extracellular signals in an autocrine and paracrine...
4.
Pernot S, Tome M, Galeano-Otero I, Evrard S, Badiola I, Delom F, et al.
Front Immunol . 2024 Jan; 14:1278630. PMID: 38250065
The overexpression of the immunoinhibitory receptor programmed death-1 (PD1) on T-cells is involved in immune evasion in cancer. The use of anti-PD-1/PDL-1 strategy has deeply changed the therapies of cancers...
5.
Mehranzadeh E, Crende O, Badiola I, Garcia-Gallastegi P
Biomedicines . 2022 Dec; 10(12). PMID: 36552048
Protein convertases (PCs) play a significant role in post-translational procedures by transforming inactive precursor proteins into their active forms. The role of PCs is crucial for cellular homeostasis because they...
6.
Francois A, Descarpentrie J, Badiola I, Siegfried G, Evrard S, Pernot S, et al.
Br J Cancer . 2022 Dec; 128(7):1189-1195. PMID: 36522477
Immunotherapy is becoming an advanced clinical management for various cancers. Rebuilding of aberrant immune surveillance on cancers has achieved notable progress in the past years by either in vivo or...
7.
Velado-Eguskiza A, Gomez-Santos L, Badiola I, Saez F, Alonso E
Cancers (Basel) . 2022 Apr; 14(7). PMID: 35406405
Testicular Germ Cell Tumours (TGCT) are widely considered a "curable cancer" due to their exceptionally high survival rate, even if it is reduced by many years after the diagnosis due...
8.
Descarpentrie J, Arauzo-Bravo M, He Z, Francois A, Gonzalez A, Garcia-Gallastegi P, et al.
Cancers (Basel) . 2022 Mar; 14(5). PMID: 35267511
Proprotein convertases or PCs are known to regulate the malignant phenotype of colon cancer cells by different mechanisms, but their effects on cancer stem cells (CSCs) have been less widely...
9.
Gerovska D, Garcia-Gallastegi P, Crende O, Marquez J, Larrinaga G, Unzurrunzaga M, et al.
Int J Mol Sci . 2021 Jun; 22(9). PMID: 34062897
Cancer is a phenomenon broadly related to ageing in various ways such as cell cycle deregulation, metabolic defects or telomerases dysfunction as principal processes. Although the tumor cell is the...
10.
Lopez J, Siegfried G, Cantonero C, Soulet F, Descarpentrie J, Smani T, et al.
Cancers (Basel) . 2021 Apr; 13(7). PMID: 33916304
The intracellular calcium concentration ([Ca]) modulation plays a key role in the regulation of cellular growth and survival in normal cells and failure of [Ca] homeostasis is involved in tumor...