Igor Pottosin
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Explore the profile of Igor Pottosin including associated specialties, affiliations and a list of published articles.
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46
Citations
1179
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Recent Articles
1.
Pottosin I, Dobrovinskaya O
Stress Biol
. 2023 Sep;
2(1):31.
PMID: 37676554
Two-pore cation channel, TPC1, is ubiquitous in the vacuolar membrane of terrestrial plants and mediates the long distance signaling upon biotic and abiotic stresses. It possesses a wide pore, which...
2.
Olivas-Aguirre M, Cruz-Aguilar L, Pottosin I, Dobrovinskaya O
Cells
. 2023 Aug;
12(16).
PMID: 37626875
Degranulation mediated killing mechanism by NK cells is dependent on store-operated Ca entry (SOCE) and has optimum at moderate intracellular Ca elevations so that partial block of SOCE optimizes the...
3.
Pottosin I, Olivas-Aguirre M, Dobrovinskaya O
J Leukoc Biol
. 2023 Apr;
114(1):21-41.
PMID: 37039524
Acute lymphoblastic leukemia with the worst prognosis is related to minimal residual disease. Minimal residual disease not only depends on the individual peculiarities of leukemic clones but also reflects the...
4.
Olivas-Aguirre M, Perez-Chavez J, Torres-Lopez L, Hernandez-Cruz A, Pottosin I, Dobrovinskaya O
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672393
ALL is a highly aggressive subtype of leukemia that affects children and adults. Glucocorticoids (GCs) are a critical component of the chemotherapeutic strategy against T-ALL. Cases of resistance to GC...
5.
Olivas-Aguirre M, Torres-Lopez L, Villatoro-Gomez K, Perez-Tapia S, Pottosin I, Dobrovinskaya O
Pharmaceuticals (Basel)
. 2022 Mar;
15(3).
PMID: 35337163
Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses the development of cancer in both in vitro (cancer cell culture)...
6.
Olivas-Aguirre M, Torres-Lopez L, Gomez-Sandoval Z, Villatoro-Gomez K, Pottosin I, Dobrovinskaya O
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445394
Cytotoxic effects of cannabidiol (CBD) and tamoxifen (TAM) have been observed in several cancer types. We have recently shown that CBD primarily targets mitochondria, inducing a stable mitochondrial permeability transition...
7.
Olivas-Aguirre M, Torres-Lopez L, Pottosin I, Dobrovinskaya O
Front Oncol
. 2021 Mar;
11:617937.
PMID: 33777761
Glucocorticoids (GCs) are a central component of multi-drug treatment protocols against T and B acute lymphoblastic leukemia (ALL), which are used intensively during the remission induction to rapidly eliminate the...
8.
Pottosin I, Olivas-Aguirre M, Dobrovinskaya O, Zepeda-Jazo I, Shabala S
Front Plant Sci
. 2021 Feb;
11:616077.
PMID: 33574826
This work critically discusses the direct and indirect effects of natural polyamines and their catabolites such as reactive oxygen species and γ-aminobutyric acid on the activity of key plant ion-transporting...
9.
Olivas-Aguirre M, Torres-Lopez L, Pottosin I, Dobrovinskaya O
Int J Mol Sci
. 2020 Dec;
22(1).
PMID: 33379175
Anticancer activity of different phenols is documented, but underlying mechanisms remain elusive. Recently, we have shown that cannabidiol kills the cells of acute lymphoblastic leukemia (ALL) by a direct interaction...
10.
Valle-Reyes S, Dobrovinskaya O, Pottosin I
Cell Physiol Biochem
. 2020 Sep;
54(5):842-852.
PMID: 32886870
Background/aims: Kv1.3 channel is the only voltage-dependent potassium channel in plasma membrane of human lymphocytes. Bearing in mind a rather steep voltage-dependence of Kv1.3 activation and inactivation, its modulation by...