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Ibrahim A Aljuffali

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Articles 70
Citations 716
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Recent Articles
1.
Binkhathlan Z, Yusuf O, Ali R, Alomrani A, Alshamsan A, Alshememry A, et al.
Int J Pharm X . 2024 Jun; 7:100253. PMID: 38845681
This study aimed to present findings on a paclitaxel (PTX)-loaded polymeric micellar formulation based on polycaprolactone-vitamin E TPGS (PCL-TPGS) and evaluate its in vitro anticancer activity as well as its...
2.
Lin Z, Hung C, Aljuffali I, Lin M, Fang J
Drug Des Devel Ther . 2024 Apr; 18:1277-1296. PMID: 38681207
Psoriasis presents as a complex genetic skin disorder, characterized by the interaction between infiltrated immune cells and keratinocytes. Substantial progress has been made in understanding the molecular mechanisms of both...
3.
Tang K, Hsu C, Aljuffali I, Alalaiwe A, Lai W, Gu P, et al.
Biomed Pharmacother . 2023 Dec; 170:116073. PMID: 38159374
Atopic dermatitis (AD) is one of the most common skin autoimmune diseases needing continuous anti-inflammatory management. Pterostilbene is reported to exhibit anti-inflammatory activity with higher bioavailability and stability than its...
4.
Aljuffali I, Anwer M, Ahmed M, Alalaiwe A, Aldawsari M, Fatima F, et al.
Pharmaceuticals (Basel) . 2023 Nov; 16(11). PMID: 38004415
In the current study, the toxic effects of gefitinib-loaded solid lipid nanoparticles (GFT-loaded SLNs) upon human breast cancer cell lines (MCF-7) were investigated. GFT-loaded SLNs were prepared through a single...
5.
Yang S, Lin C, Alshetaili A, Aljuffali I, Chien M, Fang J
Biomed Pharmacother . 2023 Jun; 165:115017. PMID: 37327588
The emergence of multidrug-resistant bacteria contributes to the necessity of developing novel infection treatment approaches. This study was designed to evaluate the antimicrobial and wound healing activities of platelet-rich plasma...
6.
Anwer M, Ahmed M, Aldawsari M, Iqbal M, Soliman G, Aljuffali I
Pharmaceutics . 2023 May; 15(5). PMID: 37242700
Eluxadoline (ELD), a recently approved drug, exhibits potential therapeutic effects in the management and treatment of IBS-D. However, its applications have been limited due to poor aqueous solubility, leading to...
7.
Lin Y, Hsiao C, Alshetaili A, Aljuffali I, Chen E, Fang J
Eur J Pharm Sci . 2023 May; 186:106458. PMID: 37137418
The present study screened the utility of topically-applied nanoformulations to target the drugs/actives into the skin reservoir with the reduction of possible systemic absorption. The lipid-based nanoformulations selected in this...
8.
Yang S, Alalaiwe A, Lin Z, Lin Y, Aljuffali I, Fang J
Biomolecules . 2022 Aug; 12(8). PMID: 36008966
Skin inflammation occurs due to immune dysregulation because of internal disorders, infections, and allergic reactions. The inflammation of the skin is a major sign of chronic autoimmune inflammatory diseases, such...
9.
Aljuffali I, Lin C, Yang S, Alalaiwe A, Fang J
AAPS PharmSciTech . 2022 Jul; 23(6):187. PMID: 35798907
Tea catechins are a group of flavonoids that show many bioactivities. Catechins have been extensively reported as a potential treatment for skin disorders, including skin cancers, acne, photoaging, cutaneous wounds,...
10.
Tseng C, Lin C, Aljuffali I, Huang J, Yang S, Fang J
Int J Pharm . 2022 Mar; 617:121629. PMID: 35245633
This study was conducted to appraise the possible potential of synthetic isoflavones (SIFs) on psoriasis treatment. A practical and easy-to-operate approach was employed in synthesizing a series of SIFs, considering...