Iannis Talianidis
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Explore the profile of Iannis Talianidis including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
2497
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Recent Articles
1.
Galanopoulou O, Tachmatzidi E, Deligianni E, Botskaris D, Nikolaou K, Gargani S, et al.
Nat Commun
. 2024 Jul;
15(1):5843.
PMID: 38992049
Setd8 regulates transcription elongation, mitotic DNA condensation, DNA damage response and replication licensing. Here we show that, in mitogen-stimulated liver-specific Setd8-KO mice, most of the hepatocytes are eliminated by necrosis...
2.
Tachmatzidi E, Galanopoulou O, Talianidis I
Cells
. 2021 Aug;
10(8).
PMID: 34440795
During liver organogenesis, cellular transcriptional profiles are constantly reshaped by the action of hepatic transcriptional regulators, including FoxA1-3, GATA4/6, HNF1α/β, HNF4α, HNF6, OC-2, C/EBPα/β, Hex, and Prox1. These factors are...
3.
Kontaki H, Koukaki M, Vasilarou M, Giakountis A, Deligianni E, Luo X, et al.
iScience
. 2021 Jun;
24(5):102473.
PMID: 34113819
The oncogenic function of suppressor of variegation, enhancer of zeste and MYeloid-Nervy-DEAF1-domain family methyltransferase Smyd3 has been implicated in various malignancies, including hepatocellular carcinoma (HCC). Here, we show that targeting...
4.
Papathanasiou M, Tsiftsoglou S, Polyzos A, Papadopoulou D, Valakos D, Klagkou E, et al.
EMBO J
. 2020 Oct;
40(1):e102236.
PMID: 33034061
The generation of induced pluripotent stem cells (iPSCs) from somatic cells provides an excellent model to study mechanisms of transcription factor-induced global alterations of the epigenome and genome function. Here,...
5.
Karagianni P, Moulos P, Schmidt D, Odom D, Talianidis I
Cell Rep
. 2020 Feb;
30(5):1319-1328.e6.
PMID: 32023452
Transcription factor binding to enhancer and promoter regions critical for homeostatic adult gene activation is established during development. To understand how cell-specific gene expression patterns are generated, we study the...
6.
Nikolaou K, Moulos P, Harokopos V, Chalepakis G, Talianidis I
Cell Rep
. 2017 Jul;
20(4):909-922.
PMID: 28746875
H4K20 monomethylation maintains genome integrity by regulating proper mitotic condensation, DNA damage response, and replication licensing. Here, we show that, in non-dividing hepatic cells, H4K20Me1 is specifically enriched in active...
7.
Le Guevel R, Oger F, Martinez-Jimenez C, Bizot M, Gheeraert C, Firmin F, et al.
ACS Chem Biol
. 2017 Jan;
12(3):654-663.
PMID: 28059499
Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII/NR2F2) is an orphan member of the nuclear receptor family of transcription factors whose activities are modulated upon binding of small molecules into an...
8.
Giakountis A, Moulos P, Sarris M, Hatzis P, Talianidis I
Semin Cancer Biol
. 2016 Aug;
42:70-80.
PMID: 27554136
SMYD3 is a member of the SET and MYND-domain family of methyl-transferases, the increased expression of which correlates with poor prognosis in various types of cancer. In liver and colon...
9.
Nikolaou K, Talianidis I
Mol Cell Oncol
. 2016 Jun;
3(1):e1021946.
PMID: 27308536
Cancer stem cells (CSCs) are defined as cells within tumors that can self-renew and differentiate into heterogeneous lineages of cancerous cells. The origin of CSCs is not well understood. Recent...
10.
Elkouris M, Kontaki H, Stavropoulos A, Antonoglou A, Nikolaou K, Samiotaki M, et al.
Cell Rep
. 2016 Jun;
15(12):2733-44.
PMID: 27292644
TGF-β signaling regulates a variety of cellular processes, including proliferation, apoptosis, differentiation, immune responses, and fibrogenesis. Here, we describe a lysine methylation-mediated mechanism that controls the pro-fibrogenic activity of TGF-β....