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Ian R Harmon

Explore the profile of Ian R Harmon including associated specialties, affiliations and a list of published articles. Areas
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Citations 206
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Recent Articles
1.
Dluzniewska J, Zou L, Harmon I, Ellingson M, Peterson E
Eur J Immunol . 2007 Oct; 37(11):3208-19. PMID: 17948263
Adhesion- and degranulation-promoting adaptor protein (ADAP) modulates T cell development and function and promotes TCR signaling. Regulation of ADAP protein expression during thymopoiesis and in development of other hematopoietic lineages...
2.
Will W, Aaker J, Burchill M, Harmon I, ONeil J, Goetz C, et al.
J Immunol . 2006 Mar; 176(6):3350-5. PMID: 16517702
Allelic exclusion prevents pre-B cells from generating more than one functional H chain, thereby ensuring the formation of a unique pre-BCR. The signaling processes underlying allelic exclusion are not clearly...
3.
Goetz C, Harmon I, ONeil J, Burchill M, Johanns T, Farrar M
J Immunol . 2005 Jun; 174(12):7753-63. PMID: 15944278
The molecular mechanisms regulating lymphocyte lineage commitment remain poorly characterized. To explore the role of the IL7R in this process, we generated transgenic mice that express a constitutively active form...
4.
Goetz C, Harmon I, ONeil J, Burchill M, Farrar M
J Immunol . 2004 Apr; 172(8):4770-8. PMID: 15067053
Signals initiated by the IL7R are required for B cell development. However, the roles that distinct IL7R-induced signaling pathways play in this process remains unclear. To identify the function of...
5.
Burchill M, Goetz C, Prlic M, ONeil J, Harmon I, Bensinger S, et al.
J Immunol . 2003 Nov; 171(11):5853-64. PMID: 14634095
Using transgenic mice that express a constitutively active version of STAT5b, we demonstrate that STAT5 plays a key role in governing B cell development and T cell homeostasis. STAT5 activation...