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Ian Mockridge

Explore the profile of Ian Mockridge including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 43
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Recent Articles
1.
Orr C, Fisher H, Yu X, Chan C, Gao Y, Duriez P, et al.
Sci Immunol . 2022 Jul; 7(73):eabm3723. PMID: 35857577
Antibodies protect from infection, underpin successful vaccines and elicit therapeutic responses in otherwise untreatable cancers and autoimmune conditions. The human IgG2 isotype displays a unique capacity to undergo disulfide shuffling...
2.
Sopp J, Peters S, Rowley T, Oldham R, James S, Mockridge I, et al.
Commun Biol . 2021 Sep; 4(1):1031. PMID: 34475514
The majority of depleting monoclonal antibody (mAb) drugs elicit responses via Fc-FcγR and Fc-C1q interactions. Optimal C1q interaction is achieved through hexameric Fc:Fc interactions at the target cell surface. Herein...
3.
Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, Kelly A
J Immunol . 2008 Feb; 180(5):2733-6. PMID: 18292489
No abstract available.
4.
Letestu R, Rawstron A, Ghia P, Villamor N, Boeckx N, Leuven N, et al.
Cytometry B Clin Cytom . 2006 Aug; 70(4):309-14. PMID: 16906588
The clinical course of patients with chronic lymphocytic leukemia (CLL) is heterogeneous with some patients requiring early therapy whereas others will not be treated for years. The evaluation of an...