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Ian M Johnston

Explore the profile of Ian M Johnston including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 112
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Recent Articles
1.
Balesaria S, Pattni S, Johnston I, Nolan J, Appleby R, Walters J
Gastroenterology . 2022 May; 163(2):517-519.e2. PMID: 35526572
No abstract available.
2.
Appleby R, Nolan J, Johnston I, Pattni S, Fox J, Walters J
BMJ Open Gastroenterol . 2017 Nov; 4(1):e000178. PMID: 29119003
Background: Bile acid diarrhoea (BAD) is a common cause of chronic diarrhoea with a population prevalence of primary BAD around 1%. Previous studies have identified associations with low levels of...
3.
Johnston I, Nolan J, Pattni S, Appleby R, Zhang J, Kennie S, et al.
Am J Gastroenterol . 2016 Feb; 111(3):423-32. PMID: 26856750
Objectives: Chronic diarrhea caused by primary bile acid diarrhea (PBAD) is a common condition. We have previously shown PBAD is associated with low fasting serum levels of the ileal hormone,...
4.
Nolan J, Johnston I, Pattni S, Dew T, Orchard T, Walters J
J Crohns Colitis . 2014 Dec; 9(2):125-31. PMID: 25518063
Background: Bile acids [BA] are usually reabsorbed by the terminal ileum, but this process is frequently abnormal in Crohn’s disease [CD]. BA malabsorption occurs, and excess colonic BA cause secretory...
5.
Zhang J, Nolan J, Kennie S, Johnston I, Dew T, Dixon P, et al.
Am J Physiol Gastrointest Liver Physiol . 2013 Mar; 304(10):G940-8. PMID: 23518683
Fibroblast growth factor 19 (FGF19) is proposed to be a negative feedback regulator of hepatic bile acid (BA) synthesis. We aimed to clarify the distribution of FGF19 expression in human...
6.
Nolan J, Johnston I, Walters J
Expert Rev Gastroenterol Hepatol . 2012 Dec; 7(1):49-56. PMID: 23265149
The role of bile acids (BA) extends far beyond lipid digestion and cholesterol metabolism. The transcriptional regulation of multiple genes within the liver and intestine are under their influence. BA...