Iain S Haslam
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Explore the profile of Iain S Haslam including associated specialties, affiliations and a list of published articles.
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31
Citations
573
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Recent Articles
1.
Palmer M, Dias I, Smart E, Benatzy Y, Haslam I
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Jun;
1868(9):159361.
PMID: 37348644
The importance of cholesterol in hair follicle biology is underscored by its links to the pathogenesis of alopecias and hair growth disorders. Reports have associated defects in ABCA5, a membrane...
2.
Palmer M, Smart E, Haslam I
Histochem Cell Biol
. 2021 Jan;
155(5):529-545.
PMID: 33404706
Cholesterol has long been suspected of influencing hair biology, with dysregulated homeostasis implicated in several disorders of hair growth and cycling. Cholesterol transport proteins play a vital role in the...
3.
Haslam I, Paus R
Bioessays
. 2020 Sep;
42(11):e2000053.
PMID: 32984997
Skin is a comparatively accessible organ possessing many conserved regulatory and signaling pathways, drawing researchers from varied fields toward its study. Hair follicle (HF) biology in particular has expanded rapidly...
4.
Haslam I, Zhou G, Xie G, Teng X, Ao X, Yan Z, et al.
J Invest Dermatol
. 2020 Jul;
141(2):334-344.
PMID: 32682910
Chemotherapy-induced hair loss (alopecia) (CIA) remains a major unsolved problem in clinical oncology. CIA is often considered to be a consequence of the antimitotic and apoptosis-promoting properties of chemotherapy drugs...
5.
El-Chami C, Haslam I, Steward M, ONeill C
Sci Rep
. 2020 May;
10(1):8639.
PMID: 32433593
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Smart E, Farjo N, Farjo B, Haslam I, Paus R
J Dermatol Sci
. 2019 Jul;
95(1):44-47.
PMID: 31272852
No abstract available.
7.
Palmer M, Blakeborough L, Harries M, Haslam I
Exp Dermatol
. 2019 Jul;
29(3):299-311.
PMID: 31260136
Lipids and lipid metabolism are critical factors in hair follicle (HF) biology, and cholesterol has long been suspected of influencing hair growth. Altered cholesterol homeostasis is involved in the pathogenesis...
8.
Haslam I, Smart E
Biomark Insights
. 2019 May;
14:1177271919842180.
PMID: 31037027
Damage to hair follicles following exposure to toxic chemotherapeutics can cause substantial hair loss, commonly known as chemotherapy-induced alopecia (CIA). Preventive therapies remain limited; however, recent advances in the use...
9.
Hawkshaw N, Hardman J, Haslam I, Shahmalak A, Gilhar A, Lim X, et al.
PLoS Biol
. 2018 May;
16(5):e2003705.
PMID: 29738529
Hair growth disorders often carry a major psychological burden. Therefore, more effective human hair growth-modulatory agents urgently need to be developed. Here, we used the hypertrichosis-inducing immunosuppressant, Cyclosporine A (CsA),...
10.
El-Chami C, Haslam I, Steward M, ONeill C
Sci Rep
. 2018 Mar;
8(1):5167.
PMID: 29581434
Epidermal barrier function is provided by the highly keratinised stratum corneum and also by tight junctions (TJs) in the granular layer of skin. The development of the TJ barrier significantly...