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I Spier

Explore the profile of I Spier including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 28
Followers 0
Related Specialties
General Medicine
Oncology
Public Health
Top 10 Co-Authors
S Aretz
P Maier
F Wenz
S Fruehauf
R Huneburg
W J Zeller
S Laufs
M Zucknick
M Berger
C P Strassburg
Published In
Internist (Berl)
Educ Med Salud
Cancer Gene Ther
Gene Ther
Endosc Int Open
Affiliations
Soon will be listed here.
Recent Articles
1.
[Gastrointestinal polyposis syndromes]
Spier I, Huneburg R, Aretz S
Internist (Berl) . 2020 Nov; 62(2):133-144. PMID: 33237439
Background: Gastrointestinal polyposis syndromes are the second most common cause of hereditary colorectal carcinomas after Lynch syndrome (hereditary non-polyposis colon cancer, HNPCC). The detection of a causal germline mutation in...
2.
Dye chromoendoscopy leads to a higher adenoma detection in the duodenum and stomach in patients with familial adenomatous polyposis
Huneburg R, Heling D, Kaczmarek D, van Heteren P, Olthaus M, Fimmers R, et al.
Endosc Int Open . 2020 Oct; 8(10):E1308-E1314. PMID: 33015332
 Duodenal cancer is the cancer most often seen in patients with familial adenomatous polyposis (FAP) who have undergone risk-reducing colonic surgery. Almost all patients with FAP eventually develop duodenal adenomas...
3.
F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells
Maier P, Heckmann D, Spier I, Laufs S, Zucknick M, Allgayer H, et al.
Cancer Gene Ther . 2012 Oct; 19(11):802-10. PMID: 23037811
Chemoprotection of haematopoietic stem cells (HSCs) by gene therapeutic transfer of drug-resistance genes represents the encouraging approach to prevent myelosuppression, which is one of the most severe side effects in...
4.
[Gastrointestinal polyposis syndromes]
Spier I, Aretz S
Internist (Berl) . 2012 Mar; 53(4):371-2, 374-6, 378-80 passim. PMID: 22430643
Hereditary gastrointestinal polyposis syndromes account for around 1% of all colorectal cancers; most of them are associated with a broad spectrum of extracolonic tumors. The initial diagnosis is based on...
5.
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K)
Maier P, Spier I, Laufs S, Veldwijk M, Fruehauf S, Wenz F, et al.
Gene Ther . 2009 Oct; 17(3):389-99. PMID: 19865182
Myelotoxicity is a dose-limiting effect of many chemotherapeutic regimens. Thus, there is great interest in protecting human hematopoietic stem cells by the transfer of drug resistance genes. The main focus...
6.
[Experiences and attitudes of medical students in relation to psychiatry]
Eizirik C, de Abreu P, da Fonseca A, Caleffi L, Rocha D, Spier I, et al.
Educ Med Salud . 1990 Oct; 24(4):424-39. PMID: 2090455
No abstract available.