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I S Lossos

Explore the profile of I S Lossos including associated specialties, affiliations and a list of published articles. Areas
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Articles 84
Citations 3598
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Recent Articles
1.
Guo X, Koff J, Moffitt A, Cinar M, Ramachandiran S, Chen Z, et al.
Oncogene . 2017 Apr; 36(29):4224-4232. PMID: 28368397
Diffuse large B-cell lymphoma (DLBCL) has been categorized into two molecular subtypes that have prognostic significance, namely germinal center B-cell like (GCB) and activated B-cell like (ABC). Although ABC-DLBCL has...
2.
Chapman J, Gentles A, Sujoy V, Vega F, Dumur C, Blevins T, et al.
Leukemia . 2015 Apr; 29(11):2270-3. PMID: 25921246
No abstract available.
3.
Zhu D, Bhatt S, Lu X, Guo F, Veelken H, Hsu D, et al.
Leukemia . 2015 Feb; 29(7):1587-99. PMID: 25676418
The pathogenesis of Chlamydophila psittaci-negative ocular adnexal extranodal marginal zone lymphomas (OAEMZLs) is poorly understood. OAEMZLs are monoclonal tumors expressing a biased repertoire of mutated surface immunoglobulins. Antigenic activation of...
4.
Dagklis A, Ponzoni M, Govi S, Cangi M, Pasini E, Charlotte F, et al.
Leukemia . 2011 Oct; 26(4):814-21. PMID: 22024723
Evidence from certain geographical areas links lymphomas of the ocular adnexa marginal zone B-cell lymphomas (OAMZL) with Chlamydophila psittaci (Cp) infection, suggesting that lymphoma development is dependent upon chronic stimulation...
5.
Azambuja D, Natkunam Y, Biasoli I, Lossos I, Anderson M, Morais J, et al.
Ann Oncol . 2011 May; 23(3):736-742. PMID: 21602260
Background: A recent study demonstrated that an increased number of CD68+ macrophages were correlated with primary treatment failure, shortened progression-free survival (PFS) and disease-specific survival (DSS) in patients with classical...
6.
Han H, Escalon M, Hsiao B, Serafini A, Lossos I
Ann Oncol . 2008 Oct; 20(2):309-18. PMID: 18842613
Background: Positron emission tomography (PET) is a powerful predictor of relapse and survival in non-Hodgkin's lymphomas (NHLs) based on studies carried out in the prerituximab era. Little is known about...
7.
Lossos I
Leukemia . 2005 May; 19(8):1331-3. PMID: 15902286
No abstract available.
8.
Chen D, Padiernos E, Ding F, Lossos I, Lopez C
Cell Death Differ . 2004 Dec; 12(4):358-68. PMID: 15592436
The p53 pathway is a central apoptotic regulator. Deregulation of the Rb/E2F pathway occurs in a majority of tumors, resulting in both unrestrained proliferation and enhanced apoptosis sensitivity via p53-dependent...
9.
Lossos I, Levy R, Alizadeh A
Leukemia . 2004 Sep; 18(11):1775-9. PMID: 15385936
Activation-induced cytidine deaminase (AID), highly expressed in germinal center (GC)-lymphocytes, is involved in somatic hypermutation (SHM). We examined AID expression in diffuse large B-cell lymphomas (DLBCL) of germinal center B-cell...
10.
Lossos I, Akasaka T, Martinez-Climent J, Siebert R, Levy R
Leukemia . 2003 Jul; 17(7):1390-7. PMID: 12835729
The BCL6 gene, which functions as a transcription repressor, is the target of multiple chromosomal translocations in non-Hodgkin's lymphomas (NHL). These translocations occur in the nontranslated region of the BCL6...