I P Touw
Overview
Explore the profile of I P Touw including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
69
Citations
868
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Alemdehy M, de Looper H, Kavelaars F, Sanders M, Hoogenboezem R, Lowenberg B, et al.
Leukemia
. 2016 Jul;
30(11):2238-2241.
PMID: 27363282
No abstract available.
2.
Gits J, van Leeuwen D, Carroll H, Touw I, Ward A
Leukemia
. 2006 Oct;
20(12):2111-8.
PMID: 17066093
Mutations in the granulocyte colony-stimulating factor receptor (G-CSF-R) gene leading to a truncated protein have been identified in a cohort of neutropenia patients highly predisposed to acute myeloid leukemia. Such...
3.
Erkeland S, Aarts L, Irandoust M, Roovers O, Klomp A, Valkhof M, et al.
Oncogene
. 2006 Sep;
26(14):1985-94.
PMID: 17001306
Signals induced by granulocyte colony-stimulating factor (G-CSF), the major cytokine involved in neutrophil development, are tightly controlled by ligand-induced receptor internalization. Truncated G-CSF receptors (G-CSF-Rs) that fail to internalize show...
4.
van de Geijn G, Aarts L, Erkeland S, Prasher J, Touw I
Rev Physiol Biochem Pharmacol
. 2003 Apr;
149:53-71.
PMID: 12687405
Hematopoiesis, the process of blood cell formation, is orchestrated by cytokines and growth factors that stimulate the expansion of different progenitor cell subsets and regulate their survival and differentiation into...
5.
Oomen S, Ward A, Hofland L, Lamberts S, Lowenberg B, Touw I
Hematol J
. 2002 Mar;
2(5):322-9.
PMID: 11920268
Introduction: Somatostatin, originally identified as a peptide involved in neurotransmission, functions as an inhibitor of multiple cellular responses, including hormonal secretion and proliferation. Somatostatin acts through activation of G-protein-coupled receptors...
6.
de Koning J, Ward A, Caldenhoven E, de Groot R, Lowenberg B, Touw I
Hematol J
. 2002 Mar;
1(4):220-5.
PMID: 11920194
Introduction: Activation of the signal transducer and activator of transcription protein STAT3 is a crucial step in granulocyte colony-stimulating factor (G-CSF)-mediated cell cycle exit and subsequent neutrophilic differentiation of myeloid...
7.
Dong F, Qiu Y, Yi T, Touw I, Larner A
J Immunol
. 2001 Nov;
167(11):6447-52.
PMID: 11714811
The G-CSF receptor transduces signals that regulate the proliferation, differentiation, and survival of myeloid cells. A subgroup of patients with severe congenital neutropenia (SCN) has been shown to harbor mutations...
8.
Oomen S, Hofland L, Lamberts S, Lowenberg B, Touw I
FEBS Lett
. 2001 Aug;
503(2-3):163-7.
PMID: 11513875
The regulatory peptide somatostatin (SST) acts via a family of G-protein-coupled receptors comprising five subtypes (SSTR1-5). G-protein-coupled receptors activate multiple signaling mechanisms, which variably depend on internalization and intracellular routing...
9.
Wang W, Wang X, Ward A, Touw I, Friedman A
Leukemia
. 2001 May;
15(5):779-86.
PMID: 11368439
To assess cooperation between G-CSF signals and C/EBPalpha, we characterized Ba/F3 pro-B cell lines expressing C/EBPalphaWT-ER and the G-CSF receptor (GCSFR). In these lines, GCSFR signals can be evaluated independent...
10.
Oomen S, Verplanke N, Hofland J, Lamberts S, Lowenberg B, Touw I
Leukemia
. 2001 May;
15(4):621-7.
PMID: 11368365
Somatostatin, a neuropeptide with multiple activities, exerts its function via G-coupled membrane receptors. Five somatostatin receptor subtypes, sst1-5, have been identified. We have recently established that somatostatin acts as a...