I MOHR
Overview
Explore the profile of I MOHR including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
744
Followers
0
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Recent Articles
1.
Schneider R, Agol V, Andino R, Bayard F, Cavener D, Chappell S, et al.
Mol Cell Biol
. 2001 Nov;
21(23):8238-46.
PMID: 11710333
No abstract available.
2.
Taneja S, MacGregor J, Markus S, Ha S, MOHR I
Proc Natl Acad Sci U S A
. 2001 Jul;
98(15):8804-8.
PMID: 11438715
Replication-competent, attenuated herpes simplex virus-1 (HSV-1) derivatives that contain engineered mutations into the viral gamma 34.5 virulence gene have been used as oncolytic agents. However, as attenuated mutants often grow...
3.
MOHR I, Sternberg D, Ward S, Leib D, Mulvey M, Gluzman Y
J Virol
. 2001 May;
75(11):5189-96.
PMID: 11333900
We describe here the neurovirulence properties of a herpes simplex virus type 1 gamma34.5 second-site suppressor mutant. gamma34.5 mutants are nonneurovirulent in animals and fail to grow in a variety...
4.
Poppers J, Mulvey M, Khoo D, MOHR I
J Virol
. 2000 Nov;
74(23):11215-21.
PMID: 11070019
Upon activation by double-stranded RNA in virus-infected cells, the cellular PKR kinase phosphorylates the translation initiation factor eukaryotic initiation factor 2 (eIF2) and thereby inhibits protein synthesis. The gamma 34.5...
5.
Riedel H, Muckenthaler M, Gehrke S, MOHR I, Brennan K, Herrmann T, et al.
Blood
. 1999 Nov;
94(11):3915-21.
PMID: 10572108
Hereditary hemochromatosis (HH) is a common autosomal-recessive disorder of iron metabolism. More than 80% of HH patients are homozygous for a point mutation in a major histocompatibility complex (MHC) class...
6.
Mulvey M, Poppers J, Ladd A, MOHR I
J Virol
. 1999 Mar;
73(4):3375-85.
PMID: 10074192
The herpes simplex virus type 1 gamma34.5 gene product and the cellular GADD34 protein both contain similar domains that can regulate the activity of eukaryotic initiation factor 2 (eIF2), a...
7.
He B, Chou J, Brandimarti R, MOHR I, Gluzman Y, Roizman B
J Virol
. 1997 Aug;
71(8):6049-54.
PMID: 9223497
Earlier studies have shown that infection of human cells by herpes simplex virus 1 (HSV-1) results in the activation of RNA-dependent protein kinase (PKR) but that the alpha subunit of...
8.
MOHR I, Gluzman Y
EMBO J
. 1996 Sep;
15(17):4759-66.
PMID: 8887567
Novel suppressor variants of conditionally lethal HSV-1 gamma34.5 deletion mutants have been isolated which exhibit restored ability to grow on neoplastic neuronal cells. Deletion of the viral gamma34.5 genes, whose...
9.
Yang L, MOHR I, Fouts E, Lim D, Nohaile M, Botchan M
Proc Natl Acad Sci U S A
. 1993 Jun;
90(11):5086-90.
PMID: 8389467
For efficient DNA replication of papillomaviruses, only two viral-encoded proteins, E1 and E2, are required. Other proteins and factors are provided by the host cell. E2 is an enhancer of...
10.
Lentz M, Pak D, MOHR I, Botchan M
J Virol
. 1993 Mar;
67(3):1414-23.
PMID: 8382303
Bovine papillomavirus (BPV) DNA replication occurs in the nucleus of infected cells. Most enzymatic activities are carried out by host cell proteins, with the viral E1 and E2 proteins required...