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» Authors » I J Samudio

I J Samudio

Explore the profile of I J Samudio including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 2
Citations 101
Followers 0
Related Specialties
Oncology
Hematology
Top 10 Co-Authors
M Konopleva
M Andreeff
W Chen
V R Ruvolo
K Kojima
T McQueen
N Hanaoka
H Nakakuma
V Ruvolo
P Corn
Published In
Leukemia
Affiliations
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Recent Articles
1.
HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML
Zhou L, Ruvolo V, McQueen T, Chen W, Samudio I, Conneely O, et al.
Leukemia . 2012 Dec; 27(6):1358-68. PMID: 23247046
Nur77 and Nor1 are highly conserved orphan nuclear receptors. We have recently reported that nur77(-/-)nor1(-/-) mice rapidly develop acute myeloid leukemia (AML) and that Nur77 and Nor1 transcripts were universally...
2.
The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML
Kojima K, Shimanuki M, Shikami M, Samudio I, Ruvolo V, Corn P, et al.
Leukemia . 2008 Jun; 22(9):1728-36. PMID: 18548093
Activation of the phosphatidylinositol-3 kinase/Akt/mammalian target of the rapamycin (PI3K/Akt/mTOR) pathway and inactivation of wild-type p53 by murine double minute 2 homologue (Mdm2) overexpression are frequent molecular events in acute...