I J Clarke
Overview
Explore the profile of I J Clarke including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
312
Citations
2447
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Flay H, Reed C, Kuhn-Sherlock B, Phyn C, Burke C, Meier S, et al.
J Dairy Sci
. 2022 Feb;
105(4):3601-3614.
PMID: 35151482
Previous research has identified that Holstein-Friesian dairy heifers with positive (POS) genetic merit for fertility traits (FertBV) reach puberty earlier than heifers with negative (NEG) FertBV. The hypothalamus-pituitary-gonadal (HPG) axis...
2.
Smith J, Roseweir A, Millar M, Clarke I, Millar R
J Endocrinol
. 2018 Mar;
237(2):165-173.
PMID: 29549187
Kisspeptin signalling is indispensable for fertility, stimulating gonadotropin-releasing hormone (GnRH) secretion and mediating gonadal steroid feedback on GnRH neurons. Moreover, kisspeptin neurons have been implicated in other non-reproductive neuroendocrine roles....
3.
Pouchain Ribeiro Neto R, Clarke I, Conductier G
J Neuroendocrinol
. 2017 Jul;
29(10).
PMID: 28722251
The activity of the hypothalamic-pituitary gonadal axis is influenced by energy reserves, such that an increase or a decrease in adiposity may perturb the secretion and action of gonadotrophin-releasing hormone...
4.
George J, Hendrikse M, Veldhuis J, Clarke I, Anderson R, Millar R
Clin Endocrinol (Oxf)
. 2017 Feb;
86(5):731-738.
PMID: 28186349
Background: Gonadotropin-inhibitory hormone (GnIH, human homologue of RFRP-3) suppresses gonadotropin secretion in animal models, but its effects have not been studied in the human. Objective: We tested the hypotheses that...
5.
Clarke I, Arbabi L
Domest Anim Endocrinol
. 2016 Jun;
56 Suppl:S165-79.
PMID: 27345314
Gonadotropin releasing hormone is the primary driver of reproductive function and pulsatile GnRH secretion from the brain causes the synthesis and secretion of LH and FSH from the pituitary gland....
6.
Hewagalamulage S, Lee T, Clarke I, Henry B
Domest Anim Endocrinol
. 2016 Jun;
56 Suppl:S112-20.
PMID: 27345309
There is a strong inter-relationship between activation of the hypothalamo-pituitary-adrenal axis and energy homeostasis. Patients with abdominal obesity have elevated cortisol levels. Furthermore, stress and glucocorticoids act to control both...
7.
Barrell G, Ridgway M, Wellby M, Pereira A, Henry B, Clarke I
Gen Comp Endocrinol
. 2016 Feb;
229:1-7.
PMID: 26899722
Red deer are seasonal with respect to reproduction and food intake, so we tested the hypothesis that their brains would show seasonal changes in numbers of cells containing hypothalamic neuropeptides...
8.
Clarke I
Compr Physiol
. 2015 Jan;
5(1):217-53.
PMID: 25589270
The endocrine hypothalamus constitutes those cells which project to the median eminence and secrete neurohormones into the hypophysial portal blood to act on cells of the anterior pituitary gland. The...
9.
Yau S, Russo V, Clarke I, Dunshea F, Werther G, Sabin M
Int J Obes (Lond)
. 2014 Nov;
39(5):770-81.
PMID: 25370576
Background/objective: IGF-binding protein (IGFBP)-2 is the principal IGFBP produced by white adipocytes during adipogenesis, and circulating levels are reduced in obesity. Overexpression of IGFBP-2 in transgenic mice prevents obesity, but...
10.
Hewagalamulage S, Clarke I, Young I, Rao A, Henry B
J Neuroendocrinol
. 2014 Oct;
27(1):44-56.
PMID: 25315658
We have identified female sheep that have either high (HR) or low (LR) cortisol responses to adrenocorticotrophin. On a high-energy diet, HR have greater propensity to weight gain and obesity,...